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MALIGNANT TUMORS OF THE URINARY SYSTEM. 13.5% of total malignant tumors. ACC Bladder 4.4% TCC 92%. Time Trend of Cancer Bladder illustrated by Two Cancer Pathology Registries. Pathologic Classification of Transitional cell carcinoma. Papillary non-invasive TCC ~23%. Tumor cells. Pa. LP.
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MALIGNANT TUMORSOF THEURINARY SYSTEM 13.5% of total malignant tumors
ACC Bladder 4.4% TCC 92%
Time Trend of Cancer Bladder illustrated by Two Cancer Pathology Registries
Pathologic Classification of Transitional cell carcinoma Papillary non-invasive TCC ~23% Tumor cells Pa LP Invasive TCC ~77%
Correlation between Clinical & Pathologic Classification of Transitional cell carcinoma Cystoscopic examination by an experienced urologist is not a very useful tool for the assessement of the depth of invasion of urinary bladder tumors.
Time Trend of Cancer Bladder illustrated by Two Cancer Pathology Registries
MALIGNANT TUMORS OF THE MALE GENITAL SYSTEM 0.40% of total malignancy 0.48% of total malignancy • Adenocarcinoma • PIN • Undifferentiated small cell carcinoma Testicular tumors – 39 cases Prostatic Tumors – 47 cases
MALIGNANT SKIN TUMORS 3.74% of total malignant tumors
Malignant skin tumors Sites of malignant skin tumors-389 cases Head 10.3% 56.8% 3.6% Lower extr.
Malignant skin tumors Histopathologic types of malignant skin tumors-389 cases squamous Basal 45.5% 37.0% NHL5.9%
SOFT TISSUE SARCOMAS 2.74% of total malignant tumors 28.00% pediatric cases No. 3 in ranking of pediatric malignancies
Soft tissue sarcomas Sites of soft tissue sarcoms-268 cases 32.5% 14.5% 11.2%
Soft tissue sarcomas Histopathologic types of soft tissue sarcoms-268 cases 16.0% 14.9% 13.8%
MALIGNANT BONE TUMORS 1.92% of total malignant tumors 54.80% pediatric cases No. 2 in ranking of pediatric malignancies
Malignant Bone Tumors Sites of malignant bone tumors-222 cases 9.9% 10.4% 50.4%
Malignant Bone Tumors Histopathologic types of malignant bone tumors – 222 cases NHL 9.0% Myeloma 6.3% 47.7% 14.9% 17.6%
MALIGNANT ENDOCRINE SYSTEM TUMORS Formed 2.23% of total malignancies
Sites of Malignant endocrine tumors- 222 cases 65.3% 15.3% 19.4%
Malignant thyroid gland tumors M/F ratio 1:1.6 Adult cases 97.95% Histopathologic types of malignant thyroid tumors-145 cases
Malignant Adrenal gland tumors M/F ratio 2.8:1 Pediatric cases 84.44% Histopathologic types of malignant adrenal tumors– 77 cases 46.7% 44.1%
MULTIPLE MALIGNANT TUMORS Sites of multiple malignant tumors-183 cases Breast
MULTIPLE MALIGNANT TUMORS MULTIPLE MALIGNANT TUMORS – 183 cases Duct
MULTIPLE MALIGNANT TUMORS Multiple malignant tumors in different anatomic sites- 6 cases
218 cases of borderline malignancy / Low malignant potential Fibromatosis
46% 37% 32% Sites & Histopathologic typesof tumors metastatic at initial presentation– 557 cases
14% 28% 33% Sites & Histopathologic types of metastatic recurrent tumors – 249 cases
Sites of locally recurrent malignant tumors – 522 cases 34% 18% 8% 6%
Members of the Department of Pathology Surgical Pathology Unit, NCI Professor Dr. Hassan Nabil Tawfik Professor Dr. Nabil El-Bolkainy Professor Dr. Saad Eissa Professor Dr. Nadia Mokhtar Professor Dr. Nader Dahaba Professor Dr. Nayera Anwar Professor Dr. Magda Murad Professor Dr. Sumaya El-Huseiny Professor Dr. Hala Taha Professor Dr. Mustafa El-Kabany Professor Dr. Amani El-Deeb Dr. Akram Nouh Dr. Hoda Ismail Dr. Amani Abdel Hamid Dr. Mona Sakr Dr. Wael Tharwat Dr. Iman Gouda Dr. Iman Adel Dr. Tarek El-Bolkainy Dr. Asmaa Salama Dr. Iman Loay Dr. Dina Salah Dr. Nevine Fayez Dr. Safinaz Talaat Dr. Mohab Eissa No matter how good you may seem, You’re always better in a team
Special Thanks to Dept. of Biostatistics: Prof. Inas El-AttarDept. of Clinical Pathology : Prof. Azza KamelProf. Mohamed HuseinDr. Atef Badran