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Neural Plasticity or Recovery from Brain Damage

Neural Plasticity or Recovery from Brain Damage. Two Type of Neuronal Death a. Apoptosis – Active Cell Death b. Necrosis – Passive Cell Death (i.e. injury) 2. Effects of neural damage (necrosis)

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Neural Plasticity or Recovery from Brain Damage

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  1. Neural Plasticity orRecovery from Brain Damage

  2. Two Type of Neuronal Death a. Apoptosis – Active Cell Death b. Necrosis – Passive Cell Death (i.e. injury) 2. Effects of neural damage (necrosis) a. Anterograde degeneration – Involves the distal segment of the axon, recovery is possible b. Retrograde degeneration – Death of a cell, necrosis c. Transneuronal degeneration – (cascading effect) The neuron across from the injured neuron will die as well

  3. Neuronal Degeneration in Necrosis Anterograde & Retrograde

  4. Neuronal Degeneration in NecrosisTransneuronal

  5. 2. Regeneration a. Sprouting – Occurs at the tip of the terminal or as a side shoot off of an axon (i.e. collateral sprouting) b. There is no “true” regeneration in the CNS but it can occur in the PNS (i.e. true = point-to-point)

  6. Regeneration following in Central Nervous System: Collateral Sprouting

  7. Regeneration in the Peripheral Nervous System (e.g., spinal cord injuries) Point to point

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