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Photodynamic Therapy for Basal Cell Skin Cancer: Successful Cases and Recurrence-Free Periods

Explore successful cases of photodynamic therapy (PDT) for basal cell skin cancer in male and female patients, highlighting tumor necrosis, recurrence-free periods, and cosmetic outcomes.

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Photodynamic Therapy for Basal Cell Skin Cancer: Successful Cases and Recurrence-Free Periods

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  1. 0.05 mg/kg, DLI – 24 hours, dose of light – 40 J/cm2 Patient L. 83 years old, male. Before treatment Recurrent basal-cell skin cancer of the face. Tumor diameter: 10 mm Day 12 after PDT. Complete tumor necrosis. Beginning border epithelization. PDT result Recurrence-free period – 12 months Day 5 after PDT. Hemorrhages and mild edema of the tumor.

  2. 0.05 mg/kg, DLI – 24 hours, dose of light – 50 J/cm2 Patient S. 86 years old, male. PDT result CR, excellent cosmetic result. Recurrence-free period – 4 months Before treatment Multiple BCC and SCC of the face and head. 24 tumors, maximal diameter – 35 mm, thickness of 4 tumors – over 3 mm. Day 13 after PDT. Complete necrosis of all tumors. Due to close placement of the tumors, some irradiation fields overlapped, and the dose of light was doubled..

  3. 0.05 mg/kg, DLI – 24 hours, dose of light – 40 J/cm2 Patient L. 83 years old, male. Before treatment Large recurrence of basal-cell skin cancer of the nose and periorbital area. Seven recurrent tumors on the border of the scar after cryosurgery, maximal diameter – 10 mm. Day 5 after PDT. Complete tumor necrosis. Day 12 after PDT. Epithelization of skin defect under the crust PDT result Recurrence-free period – 10 months

  4. 0.05 mg/kg, DLI – 24 hours, dose of light – 50 J/cm2 Patient B. 65 years old, male. Before treatment Large recurrent basal-cell skin cancer of the face. Tumor diameter – 35 mm, tumor thickness – 6 mm. Day 5 after PDT. Complete tumor necrosis. PDT result Recurrence-free period – 4 months

  5. Foscan dose – 0.05 mg/kgdrug-light interval – 48 hours

  6. 0.05 mg/kg, DLI – 48 hours, dose of light – 40 J/cm2 Patient F. 75 years old, male. Before treatment Primary basal-cell skin cancer of the nose. Tumor size: 12x7 mm, tumor thickness: over 3 mm. PDT result Recurrence-free period – 10 months

  7. 0.05 mg/kg, DLI – 48 hours, dose of light – 50 J/cm2 Patient K. 75 years old, female. Before treatment Primary basal-cell skin cancer of the nose. Tumor diameter – 12 mm, tumor thickness: over 3 mm. Day 5 after PDT Complete necrosis of the tumor PDT result Recurrence-free period – 7 months

  8. 0.05 mg/kg, DLI – 48 hours, dose of light – 50 J/cm2 Patient S. 61 years old, male. Before treatment Recurrent basal-cell skin cancer of the auricle. Tumor dimensions – 30x25mm. PDT result Recurrence-free period – 4 months

  9. 0.05 mg/kg, DLI – 48 hours, dose of light – 100 J/cm2 Patient S. 87 years old, male. Before treatment Solid primary basal-cell skin cancer of the head. Tumor diameter: 17 mm, Tumor thickness: 4 mm. 2 days after PDT. Complete tumor necrosis. 34 days after PDT. Partial wound healing. PDT result CR, good cosmetic result. Recurrence-free period – 6 months

  10. 0.05 mg/kg, DLI – 48 hours, dose of light – 100 J/cm2 Patient C. 56 years old, male. Before treatment Primary basal-cell skin cancer of periorbital area. Interfluent tumors occupy total area 20x12 mm, tumor thickness: over 3 mm. PDT result Recurrence-free period – 4 months

  11. Foscan dose – 0.04 mg/kgdrug-light interval – 24 hours

  12. 0.04 mg/kg, DLI – 24 hours, dose of light – 40 J/cm2 Patient B. 68 years old, male. Before treatment Multiple basal-cell skin cancer of the head, chest, back, arms. A total of 23 tumors, maximum tumor size: 25 mm, thickness of 4 tumors exceeded 3 mm. Day 13 after PDT. Complete necrosis of all tumors. PDT result Recurrence-free period – 7 months

  13. 0.04 mg/kg, DLI – 24 hours, dose of light – 50 J/cm2 Patient R. 75 years old, female. Before treatment Primary basal-cell skin cancer of periorbital area. Tumor diameter – 7 mm. PDT result Recurrence-free period – 7 months

  14. 0.04 mg/kg, DLI – 24 hours, dose of light – 60 J/cm2 Patient S. 78 years old, male. Before treatment Primary basal-cell skin cancer of periorbital area. Tumor diameter – 15 mm. PDT result Recurrence-free period – 7 months

  15. 0.04 mg/kg, DLI – 24 hours, dose of light – 100 J/cm2 Patient M. 68 years old, female. Day 8 after PDT. Complete tumor necrosis. PDT result Recurrence-free period – 8 months Before treatment Recurrent basal-cell skin cancer of left periorbital area. Multiple tumors, maximum diameter: 10 mm.

  16. Foscan dose – 0.03 mg/kgdrug-light interval – 24 hours

  17. 0.03 mg/kg, DLI – 24 hours, dose of light – 80 J/cm2 Patient M. 69 years old, male. Day 7 after PDT. Hemorrhagic necrosis. Before treatment Recurrent basal-cell skin cancer of left retroauricularis area. Tumor size: 18 mm. PDT result Recurrence-free period – 8 months

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