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INTERACTION OF NANO-PARITCLES WITH THE LUNG Peter Gehr Institute for Anatomy, University of Bern

INTERACTION OF NANO-PARITCLES WITH THE LUNG Peter Gehr Institute for Anatomy, University of Bern. 38th Joint Meeting Special Session on Nanoparticles Paris OECD Headquarters 7th June, 2005. S. Tschanz. Macrophages in vitro : Laser Scanning Microscopy. without particles. [% of cells].

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INTERACTION OF NANO-PARITCLES WITH THE LUNG Peter Gehr Institute for Anatomy, University of Bern

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  1. INTERACTION OF NANO-PARITCLES WITH THE LUNG Peter GehrInstitute for Anatomy, University of Bern 38th Joint Meeting Special Session on Nanoparticles Paris OECD Headquarters 7th June, 2005

  2. S. Tschanz

  3. Macrophages in vitro: Laser Scanning Microscopy without particles [% of cells] 100 with particles 50 0 + cyt. D control + cytochalasin D control F-Actin 1-mm polystyrene particles without particles [% of cells] 100 with particles 0.2-mm polystyrene particles 50 0 control + cyt. D without particles [% of cells] 100 with particles 78-nm polystyrene particles 50 0 control + cyt. D B. Rothen-Rutishauser, published in Geiser et al., 2005. Environ Health Perspect: doi:10.1289/ehp.8006.

  4. 1-mm particles 0.2-mm particles 78-nm particles 20-nm particles Autofluo-rescence 0.2-mm B. Rothen-Rutishauser, published in Geiser et al., 2005. Environ Health Perspect: doi:10.1289/ehp.8006.

  5. Red Blood Cells in vivo: Analytical Transmission Electron Microscopy Titanium Dioxide, ~30 nm 40 counts [x104] 34 N. Kapp 450 550 Energy Loss [eV] 500 nm N. Kapp E.R. Weibel Geiser et al., 2005. Environ Health Perspect: doi:10.1289/ehp.8006.

  6. Acknowledgements Bern, Institute of Anatomy: Barbara Rothen-Rutishauser Marianne Geiser Stephen Kiama Gitahi Nadine Kapp Barbara Kupferschmid Sandra Frank Barbara Tschirren Beat Haenni Bern, University Hospital: Vinzenz Im Hof University of Calgary: Samuel Schürch GSF-Neuherberg/Munich, Institute for Inhalation Biology: Joachim Heyder Wolfgang Kreyling Holger Schulz Supported by the Swiss National Science Foundation, the Silva Casa Foundation and the Swiss Agency for the Environment, Forests and Landscape (SAEFL/BUWAL)

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