The University of Chicago Institute for Translational Medicine

1. The University of Chicago Institute for Translational Medicine What Your CTSA Can Do for You! Julian Solway, MD ITM Director

2. NCRR-funded Consortium of 55 CTSAs

3. NorthShore University HealthSystem Argonne National Laboratory Illinois Institute of Technology CTSA Solway/Ross CTSA Advisory Boards, esp CARC Comp. Cancer Center Center for Medical Ethics INSTITUTE FOR TRANSLATIONAL MEDICINE Solway/Ross (Gomez/Pollack) UHI Clinical Trials Cluster Schilsky/Cohn/ Stadler Community Translational Science Cluster Burnet/Miller/Ewigman CHeSS CIHDR CHAS IGSB Advocate ACCESS Population Sciences Cluster Thisted/Ross Core Support & Technology Cluster Weiss Training Cluster Beyer/Meltzer/Olopade COMMITTEE ON CLINICAL AND TRANSLATONAL SCIENCE Meltzer (Beyer/Weichselbaum/McNally/Daum) The University of Chicago ITM/CTSA

4. What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • Research navigation – CTSA Discovery Match • Pilot and collaborative seed funding and Core lab subsidies • Clinical Resource Center • Biostatistics, study design, ethics, epidemiology advice • Bioinformatics support and advice; Community Engagement help • Plumbing behind the walls – informatics, regulatory, community • Support your multidisciplinary research with external capabilities • ResearchMatch.org • CTSAWeb.org Collaboration Opportunities • Resource identification, networking, data sharing projects underway • “C3” Chicago CTSA interactions – Community, BERD, CER, Training • Enhance Training Opportunities • Funding for two T32 graduate students (stipend plus waived tuition) per yr • $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) • MS in Health Studies aimed at fellows and junior faculty (tuition waived) • Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses • Translational Research Workshops; Pipeline programs (KKC, CSU)

5. What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • Research navigation – CTSA Discovery Match http://itm.uchicago.edu/intranet • Pilot and collaborative seed funding and Core lab subsidies • Clinical Resource Center • Biostatistics, study design, ethics, epidemiology advice • Bioinformatics support and advice; Community Engagement help • Plumbing behind the walls – informatics, regulatory, community • Support your multidisciplinary research with external capabilities • ResearchMatch.org • CTSAWeb.org Collaboration Opportunities • Resource identification, networking, data sharing projects underway • “C3” Chicago CTSA interactions – Community, BERD, CER, Training • Enhance Training Opportunities • Funding for two T32 graduate students (stipend plus waived tuition) per yr • $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) • MS in Health Studies aimed at fellows and junior faculty (tuition waived) • Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses • Translational Research Workshops; Pipeline programs (KKC, CSU)

6. What Your CTSA Can Do for You!

7. What Your CTSA Can Do for You!

8. What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • Research navigation – CTSA Discovery Match • Pilot and collaborative seed funding and Core lab subsidies • Clinical Resource Center • Biostatistics, study design, ethics, epidemiology advice • Bioinformatics support and advice; Community Engagement help • Plumbing behind the walls – informatics, regulatory, community • Support your multidisciplinary research with external capabilities • ResearchMatch.org • CTSAWeb.org Collaboration Opportunities • Resource identification, networking, data sharing projects underway • “C3” Chicago CTSA interactions – Community, BERD, CER, Training • Enhance Training Opportunities • Funding for two T32 graduate students (stipend plus waived tuition) per yr • $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) • MS in Health Studies aimed at fellows and junior faculty (tuition waived) • Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses • Translational Research Workshops; Pipeline programs (KKC, CSU)

9. What Your CTSA Can Do for You!

10. What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • Research navigation – CTSA Discovery Match • Pilot and collaborative seed funding and Core lab subsidies • Clinical Resource Center • Biostatistics, study design, ethics, epidemiology advice • Bioinformatics support and advice; Community Engagement help • Plumbing behind the walls – informatics, regulatory, community • Support your multidisciplinary research with external capabilities • ResearchMatch.org • CTSAWeb.org Collaboration Opportunities • Resource identification, networking, data sharing projects underway • “C3” Chicago CTSA interactions – Community, BERD, CER, Training • Enhance Training Opportunities • Funding for two T32 graduate students (stipend plus waived tuition) per yr • $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) • MS in Health Studies aimed at fellows and junior faculty (tuition waived) • Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses • Translational Research Workshops; Pipeline programs (KKC, CSU)

11. What Your CTSA Can Do for You! • Clinical Resource Center • Inpatient studies – intensive nursing, nutritional support, monitoring of all sorts • No hospitalization costs or routine supply costs to investigators (except industry supported research) • Outpatient studies – wide range of capabilities, including invasive procedures • Extension into community anticipated • Satellite CRC at NSUHS, less well subsidized • Laboratory services including DNA extraction and storage

12. What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • Research navigation – CTSA Discovery Match • Pilot and collaborative seed funding and Core lab subsidies • Clinical Resource Center • Biostatistics, study design, ethics, epidemiology advice • Bioinformatics support and advice; Community Engagement help • Plumbing behind the walls – informatics, regulatory, community • Support your multidisciplinary research with external capabilities • ResearchMatch.org • CTSAWeb.org Collaboration Opportunities • Resource identification, networking, data sharing projects underway • “C3” Chicago CTSA interactions – Community, BERD, CER, Training • Enhance Training Opportunities • Funding for two T32 graduate students (stipend plus waived tuition) per yr • $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) • MS in Health Studies aimed at fellows and junior faculty (tuition waived) • Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses • Translational Research Workshops; Pipeline programs (KKC, CSU)

13. What Your CTSA Can Do for You! • Biostatistics, study design, ethics, epidemiology advice • Biotime Clinic – http://biotime.uchicago.edu • Free 1 hr consultation, Tues 9–1, walk-in or appt, in Biostats Lab on MARP 3 • Research Ethics Consultation service – Dr. Lainie Ross • Adult and pediatric Research Subject Advocates • Epidemiology advice on individual basis

14. What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • Research navigation – CTSA Discovery Match • Pilot and collaborative seed funding and Core lab subsidies • Clinical Resource Center • Biostatistics, study design, ethics, epidemiology advice • Bioinformatics support and advice; Community Engagement help • Plumbing behind the walls – informatics, regulatory, community • Support your multidisciplinary research with external capabilities • ResearchMatch.org • CTSAWeb.org Collaboration Opportunities • Resource identification, networking, data sharing projects underway • “C3” Chicago CTSA interactions – Community, BERD, CER, Training • Enhance Training Opportunities • Funding for two T32 graduate students (stipend plus waived tuition) per yr • $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) • MS in Health Studies aimed at fellows and junior faculty (tuition waived) • Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses • Translational Research Workshops; Pipeline programs (KKC, CSU)

15. What Your CTSA Can Do for You! • Bioinformatics support and advice • Initiative in Biomedical Informatics (iBi) http://ibi.uchicago.edu • Wide range of genetic/genomic computation tools and expertise • REDCap research data capture system • High performance and grid computing • TraM – integrating translational data mart http://tram.uchicago.edu • and related informatics resources … • eVelos – clinical trials management system offered through UCCCC • TRIDOM – translational research initiative in the Dept of Medicine • http://tridom.bsd.uchicago.edu • HIRO – human imaging research office in the Imaging Research Institute

16. What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • Research navigation – CTSA Discovery Match • Pilot and collaborative seed funding and Core lab subsidies • Clinical Resource Center • Biostatistics, study design, ethics, epidemiology advice • Bioinformatics support and advice; Community Engagement help • Plumbing behind the walls – informatics, regulatory, community • Support your multidisciplinary research with external capabilities • ResearchMatch.org • CTSAWeb.org Collaboration Opportunities • Resource identification, networking, data sharing projects underway • “C3” Chicago CTSA interactions – Community, BERD, CER, Training • Enhance Training Opportunities • Funding for two T32 graduate students (stipend plus waived tuition) per yr • $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) • MS in Health Studies aimed at fellows and junior faculty (tuition waived) • Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses • Translational Research Workshops; Pipeline programs (KKC, CSU)

17. What Your CTSA Can Do for You! • Community Engagement help • Entrée into community through Community Connections, Center for Community Health and Vitality, interface with Chicago Dept of Public Health, NSUHS connections with Lake County Health Dept • Advice on Community-involved research and research priorities from Community Advisory and Review Council (CARC) • Practice-based research network (South Side, ACCESS, NSUHS) • Emerging relationship with Woodlawn Children’s Promise Community

18. What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • Research navigation – CTSA Discovery Match • Pilot and collaborative seed funding and Core lab subsidies • Clinical Resource Center • Biostatistics, study design, ethics, epidemiology advice • Bioinformatics support and advice; Community Engagement help • Plumbing behind the walls – informatics, regulatory, community • Support your multidisciplinary research with external capabilities • ResearchMatch.org • CTSAWeb.org Collaboration Opportunities • Resource identification, networking, data sharing projects underway • “C3” Chicago CTSA interactions – Community, BERD, CER, Training • Enhance Training Opportunities • Funding for two T32 graduate students (stipend plus waived tuition) per yr • $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) • MS in Health Studies aimed at fellows and junior faculty (tuition waived) • Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses • Translational Research Workshops; Pipeline programs (KKC, CSU)

19. What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • Research navigation – CTSA Discovery Match • Pilot and collaborative seed funding and Core lab subsidies • Clinical Resource Center • Biostatistics, study design, ethics, epidemiology advice • Bioinformatics support and advice; Community Engagement help • Plumbing behind the walls – informatics, regulatory, community • Support your multidisciplinary research with external capabilities • ResearchMatch.org • CTSAWeb.org Collaboration Opportunities • Resource identification, networking, data sharing projects underway • “C3” Chicago CTSA interactions – Community, BERD, CER, Training • Enhance Training Opportunities • Funding for two T32 graduate students (stipend plus waived tuition) per yr • $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) • MS in Health Studies aimed at fellows and junior faculty (tuition waived) • Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses • Translational Research Workshops; Pipeline programs (KKC, CSU)

20. What Your CTSA Can Do for You!

21. What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • Research navigation – CTSA Discovery Match • Pilot and collaborative seed funding and Core lab subsidies • Clinical Resource Center • Biostatistics, study design, ethics, epidemiology advice • Bioinformatics support and advice; Community Engagement help • Plumbing behind the walls – informatics, regulatory, community • Support your multidisciplinary research with external capabilities • ResearchMatch.org • CTSAWeb.org Collaboration Opportunities • Resource identification, networking, data sharing projects underway • “C3” Chicago CTSA interactions – Community, BERD, CER, Training • Enhance Training Opportunities • Funding for two T32 graduate students (stipend plus waived tuition) per yr • $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) • MS in Health Studies aimed at fellows and junior faculty (tuition waived) • Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses • Translational Research Workshops; Pipeline programs (KKC, CSU)

22. What Your CTSA Can Do for You!

23. What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • Research navigation – CTSA Discovery Match • Pilot and collaborative seed funding and Core lab subsidies • Clinical Resource Center • Biostatistics, study design, ethics, epidemiology advice • Bioinformatics support and advice; Community Engagement help • Plumbing behind the walls – informatics, regulatory, community • Support your multidisciplinary research with external capabilities • ResearchMatch.org • CTSAWeb.org Collaboration Opportunities • Resource identification, networking, data sharing projects underway • “C3” Chicago CTSA interactions – Community, BERD, CER, Training • Enhance Training Opportunities • Funding for two T32 graduate students (stipend plus waived tuition) per yr • $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) • MS in Health Studies aimed at fellows and junior faculty (tuition waived) • Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses • Translational Research Workshops; Pipeline programs (KKC, CSU)

24. What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • Research navigation – CTSA Discovery Match • Pilot and collaborative seed funding and Core lab subsidies • Clinical Resource Center • Biostatistics, study design, ethics, epidemiology advice • Bioinformatics support and advice; Community Engagement help • Plumbing behind the walls – informatics, regulatory, community • Support your multidisciplinary research with external capabilities • ResearchMatch.org • CTSAWeb.org Collaboration Opportunities • Resource identification, networking, data sharing projects underway • “C3” Chicago CTSA interactions – Community, BERD, CER, Training • Enhance Training Opportunities • Funding for two T32 graduate students (stipend plus waived tuition) per yr • $100,000 salary + fringe for four K12 Scholars per year (2 yr commitment) • MS in Health Studies aimed at fellows and junior faculty (tuition waived) • Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses • Translational Research Workshops; Pipeline programs (KKC, CSU)

25. What Your CTSA Can Do for You! • Support your multidisciplinary research with internal capabilities • Research navigation – CTSA Discovery Match • Pilot and collaborative seed funding and Core lab subsidies • Clinical Resource Center • Biostatistics, study design, ethics, epidemiology advice • Bioinformatics support and advice; Community Engagement help • Plumbing behind the walls – informatics, regulatory, community • Support your multidisciplinary research with external capabilities • ResearchMatch.org • CTSAWeb.org Collaboration Opportunities • Resource identification, networking, data sharing projects underway • “C3” Chicago CTSA interactions – Community, BERD, CER, Training • Enhance Training Opportunities • Funding for two T32 graduate students (stipend plus waived tuition) per yr • $100,000 salary + fringe for four K12 Scholars per year(2 yr commitment) • MS in Health Studies aimed at fellows and junior faculty (tuition waived) • Committee on Clinical and Translational Science with new courses • Genetic Basis of Personalized Medicine, Several Informatics Courses • Translational Research Workshops; Pipeline programs (KKC, CSU)

26. What Your CTSA Can Do for You! Questions?