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Overall Description of the Sso DNApol Molecule

Insights into DNA Replication ： The Crystal Structure of DNA Polymerase B1 from the Archaeon Sulfolobus solfataricus 學生：江承璋 學號： M93360031.

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Overall Description of the Sso DNApol Molecule

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  1. Insights into DNA Replication：The Crystal Structure of DNA Polymerase B1 from the Archaeon Sulfolobus solfataricus學生：江承璋學號：M93360031

  2. Issue： Structural page number：vol.12,2001~2008, November,2004author：C. Savino, L. Federici, V. Nastopoulos, K. A. Johnson, F. M. Pisani, M.Rossi, D. Tsernoglou PDB ID： 1S5J

  3. Structure analysisOverall Description of the Sso DNApol Molecule Finger Subdomain N-Terminal Subdomain

  4. Overall Description of the Sso DNApol Molecule

  5. BLAST&ALIGNMENT1S5J194~200a.a205~215a.a562~586a.a589~614a.a皆為a-helixBLAST&ALIGNMENT1S5J194~200a.a205~215a.a562~586a.a589~614a.a皆為a-helix

  6. Finger Subdomain

  7. (紫色) h ILE196 (粉紅) hTHR207 hMET210 hALA211 PHE218 (紅色) TYR578 LYS579 (土黃) hGLN599

  8. (粉紅) hVAL 212 hLEU215 hGLU219 (綠色) PHE 573 (紅色) LYS 581 (黃色) TYR 595

  9. (紫色) hASP192 (粉紅) PHE218 hGLU219 (綠色) THR563 THR567 hLEU570 hARG571 hPHE573 hARG574 (紅色) TYR578 LYS579

  10. helix (粉紅)PHE218 hGLU219 hVAL212 Hala211 非helix (紅色)LYS279 (綠色)PHE573

  11. N-Terminal Subdomain

  12. 謝謝大家

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