Antifungals
Antifungals. Amphotericin B Mech. Pores in ergosterol membrane. Use. Wide spectrum Aspergillus , Mucor , Candida, Cryptococcus (w/ flucytosine ), Histo , blasto , Sporothrix schenki Doesn’t cross BBB. SE. Nephrotoxicity Fever/chills, hypotension w/ IV rxn. Nystatin mech.
646 views • 45 slides