1 / 8

Tubular Secretion, Regulation of Urine Concentration and Volume

Tubular Secretion, Regulation of Urine Concentration and Volume. David and Essie. What is tubular secretion?. It is the process in which certain substances move from the plasma of blood in the peritubular capillary into the fluid of the renal tubule

dena
Download Presentation

Tubular Secretion, Regulation of Urine Concentration and Volume

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Tubular Secretion, Regulation of Urine Concentration and Volume David and Essie

  2. What is tubular secretion? • It is the process in which certain substances move from the plasma of blood in the peritubular capillary into the fluid of the renal tubule • The amount of a particular chemical excreted in the urine may exceed the amount filtered from the plasma in the glomerulus • Epithelial cells control the secretion

  3. Secretory Mechanism • The mechanism used to transport substances out = active transport • An interesting example: the epithelium of the proximal convoluted segment actively secretes certain organic compounds including penicillin, creatine, and histamine into the tubular fluid

  4. The potassium sodium pump • Potassium ions are reabsorbed actively into the proximal convoluted tube, sodium is also actively pumped

  5. Regulation of Concentration • Hormones aldosterone and ADH stimulate additional reabsorption of sodium and water • Aldosterone stimulates the distal tubule; produced in adrenal gland • ADH is produced by hypothalamus which increases water permeability in the membrane • If body fluids contain excess water, ADH secretion decreases

  6. Pictures!

  7. REVIEW QUESTIONS • What is produced by the hypothalamus that regulates urine secretion? • Answer: ADH hormone • What is the mechanism of the active transport? • Answer: sodium potassium pump • What is the tubular secretion? • Answer: secretion from plasma moves into the renal fluid • What is the other hormone that regulates urine? • Answer: aldosterone • Define active transport. • Answer: transporting something against the concentration gradient using energy

  8. THE END 

More Related