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Ontologies for vector borne diseases. Pantelis Topalis Ontology developer IMBB-FORTH, Crete Greece. Ontologies in IMBB. Anatomy of mosquitoes (and ticks) Today’s use: almost exclusively for annotation of gene expression experiments (VB). Topalis et al. IMB (2008) 17, 87-89.
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Ontologies for vector borne diseases Pantelis Topalis Ontology developer IMBB-FORTH, Crete Greece
Ontologies in IMBB Anatomy of mosquitoes (and ticks) Today’s use: almost exclusively for annotation of gene expression experiments (VB). Topalis et al. IMB (2008) 17, 87-89. Insecticide resistance ontology (and IRBase) Today’s use: driving Irbase (VB), partly MDSS (IVCC) Dialynas et al. PLOS NTD (2009) 3(6): e465. Malaria Ontology Today’s use: partly driving MDSS, DDSS Topalis et al. Malaria Journal (2010) 9, 230. RCN: Feb 25-27 2011
Decision Support Systems Data Data Data Program Data Entry Data Data Analysis Display Strategy Collection Storage Retrieval Data Management tool , XHTML files , & Sampling format , SQL data Manage - GIS software , Text files , Methodology schemes Data entry warehouse ment tool Statistical packages , GIS software , screens Modeling Google Earth , Outputs : Charts , Graphs , Maps , Tables FEEDBACK TO Interpretation PROGRAM STRATEGY & ( comparison with local historical data , relation to critical thresholds etc ) METHODOLOGY Management Decisions Decision Support Systems Our computersystems are here WHO State gov. IDOMal D. Puncher RCN: Feb 25-27 2011
PATO IDOMAL GAZ UO Soon to come in VectorBase! IDOMAL IDOMAL VBCV Linking PopGen and ontologies; Phenotypes, IR, transmission and popu- lation/ecology data
Future usage of VB ontologies • TGMA and TADS: To provide basis for cross-products (e.g. descriptions of phenotypes). • MIRO: Expansion into agricultural domain. • IDOMAL: Driving of PopGen and extended PopGen (VB), template for new Vector Borne Disease ontologies, gene annotation.