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Modified SIR for Vector-Borne Diseases

Modified SIR for Vector-Borne Diseases. Jacob Savos Katherine Kamis Colin Gay Benjamin Chua. To create a universal modified SIR model for vector-borne diseases to make predictions of the spread of diseases . Aims and Objectives.

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Modified SIR for Vector-Borne Diseases

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  1. Modified SIR for Vector-Borne Diseases Jacob Savos Katherine Kamis Colin Gay Benjamin Chua

  2. To create a universal modified SIR model for vector-borne diseases to make predictions of the spread of diseases Aims and Objectives

  3. A Vector-borne disease is transmitted by a pathogenic microorganism from an infected host to another organism • HCI will be creating a model using Dengue Fever • AOS will be creating a model using a tick-borne disease Introduction

  4. Ticks have a two-year life cycle • Ticks acquire a vector-borne disease by feeding on an infected host • Once infected, ticks transmit the disease by feeding on an uninfected host Literature Review - Ticks Lone Star Tick Deer Tick

  5. A very old disease that reemerged in the past 20 years • Transmitted via mosquito bites • In 2009, there were a total of 4452 cases of dengue fever in Singapore, of which there were 8 deaths Literature Review – Dengue Fever

  6. Aedes mosquitoes refers to the entire genus of mosquito – over 700 different species • Multiple species able to transmit dengue fever • Have characteristic black and white stripe markings on body and legs Literature Review – Aedes Mosquitoes Aedesalbopictus – the most invasive mosquito in the world Retrieved from http://www.comune.torino.it/ucstampa/2005/aedes-albopictus.jpg Aedesaegypti – Main vector of dengue fever in Singapore Retrieved from http://www.telepinar.icrt.cu/ving/images/stories/aedes-aegypti__785698.jpg

  7. Susceptible • Infected • Recovered Literature Review - SIR

  8. S’(t) = -k * S(t) * I(t) • I’(t) = -S’(t) – R’(t) • R’(t) = c * I(t) • k – Transmittal constant • c – Recovery rate SIR - Equations

  9. Begin with a simple SIR model • Develop variables needed to modify the model • Attempt to modify the model to incorporate all vector-borne diseases Methodology

  10. Timeline

  11. Academy of Science. Academy of Science Mathematics BC Calculus Text. Breish, N., & Thorne, B. (n.d.). Lyme disease and the deer tick in maryland. Maryland: The University of Maryland. Duane J. Gubler(1998, July). Clinical Microbiology Reviews, p. 480-496, Vol. 11, No. 3, 0893-8512/98/$00.00+0. Dengue and Dengue Hemorrhagic Fever. Retrieved November 3, 2010 from http://cmr.asm.org/cgi/content/full/11/3/480?view=long&pmid=9665979 Neuwirth, E., & Arganbright, D. (2004). The active modeler: mathematical modeling with Microsoft Excel. Belmont, CA: Thomson/Brooks/Cole. Ministry of Health: FAQs. (n.d.). Dengue. Retrieved November 3, 2010, from http://www.pqms.moh.gov.sg/apps/fcd_faqmain.aspx?qst=2fN7e274RAp%2bbUzLdEL%2fmJu3ZDKARR3p5Nl92FNtJidBD5aoxNkn9rR%2fqal0IQplImz2J6bJxLTsOxaRS3Xl53fcQushF2hTzrn1PirzKnZhujU%2f343A5TwKDLTU0ml2TfH7cKB%2fJRT7PPvlAlopeq%2f%2be2n%2bmrW%2bZ%2fJts8OXGBjRP3hd0qhSL4 Ong, A., Sandar, M., Chen, M. l., & Sin, L. Y. (2007). Fatal dengue hemorrhagic fever in adults during a dengue epidemic in Singapore. International Journal of Infectious Diseases, 11, 263-267. Stafford III, K. (2001). Ticks. New Haven: The Connecticut Agricultural Experiment Station. Bibliography

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