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Project Funding & New Projects

Project Funding & New Projects. Cancer Care Engineering. Project Funding. U.S. Army Medical and Materiel Command $2.3M Negotiating new $2.15M award Regenstrief Foundation $1.35M Walther Cancer Foundation $1.8M NIH (2) and DoD (1) pending. New Projects Army Funding.

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Project Funding & New Projects

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  1. Project Funding & New Projects Cancer Care Engineering

  2. Project Funding • U.S. Army Medical and Materiel Command • $2.3M • Negotiating new $2.15M award • Regenstrief Foundation • $1.35M • Walther Cancer Foundation • $1.8M • NIH (2) and DoD (1) pending

  3. New ProjectsArmy Funding • Sample Diversification • Increasing sample sites to increase power of predictive models • Population diversification • Create a Statewide Infrastructure • Partner with Clarian Health • Pilot with Clarian Arnett in Lafayette • Create a Community Research IRB

  4. New Projects in WCCEArmy Funding • Epidemiology and Visualization Project • Ebert (Purdue), Swanson and Champion (IUSCC) • Develop visual analytic tools for Indiana-based colon cancer-related epidemiological data.

  5. New Projects in WCCEArmy Funding • Molecular Characterization of CRC Samples • Stan Hamilton (MD Anderson) • Economic Evaluation of Colorectal Cancer • Mick Murray (Purdue, Regenstrief)

  6. New ProjectsWalther Embedding Program • $1M Award over 5 years • Matched by $0.5M (IUSCC and Purdue) • Objective: • Create a culture for the effective exchange of knowledge to allow clinical perspectives to drive the design of new chemistries, engineered devices/structures and mathematical predictive models that will make a critical difference in delivering effective cancer treatment.

  7. New ProjectsWalther Embedding Program • Create “Research Embedding Teams” • first year engineering or physical sciences postdoctoral fellow, • medical fellow, • Indiana University Simon Cancer Center (IUSCC) oncology faculty mentor • Purdue Physics/Chemistry/Engineering faculty mentor • Teams submit 2 page project descriptions detailing joint project. • Selected projects will be awarded: • Funds provided to cover both postdoctoral and medical fellow’s salaries • Project funds (up to $100K) • Embed physical sciences and engineering Postdoctoral Fellows in the clinics at the IUSCC • Embed medical fellows in engineering, chemistry or physics laboratories at Purdue

  8. New ProjectsGenomics of CRC • Walther Cancer Foundation • $326K over 2 years • Partnership with Notre Dame • Expression analysis on CRC tissues • Prediction of severity of the tumors • Integration of data to ID biomarkers of particularly virulent colon cancer • Overexpressed gene targets selected and functionally evaluated with RNAi based approaches

  9. Project Long Term Goals • Provide Instantaneous Communication Vehicle • Stratify Patients • Disease Risk • Prevention Strategies • Response to Therapy • Clinical Trials • ID and Validate Clinically Relevant Biomarkers • ID Therapeutic Targets • Targeted Therapies & Diagnostic Tests • ID Barriers to Effective Healthcare Delivery

  10. Cancer Care Engineering A Systems Approach to the Prevention & Treatment of Cancer Marietta Harrison harrisom@purdue.edu 765-494-1442

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