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The Research Question

A retrospective study analyzing missed prevention opportunities for stroke/TIA in UK primary care records from 2009-2013. The research aims to determine the proportion of strokes/TIAs with prior missed prevention opportunities, track changes over time, and investigate associations with patient demographics. Findings reveal suboptimal primary stroke prevention practices, with different patient profiles for anticoagulant, antihypertensive, and lipid-lowering drugs.

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The Research Question

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  1. The Research Question • Stroke is a leading cause of death and disability • Primary stroke prevention is suboptimal Aims • Calculate the proportion of strokes/TIAs with prior missed opportunities for prevention • Determine if the proportion of missed opportunities has changed over time • Investigate the association with patientor demographiccharacteristics

  2. What the Researchers Did Retrospective analysis of anonymised, electronic UK primary care records • Population • First-stroke/TIA • ≥18 years • 2009-2013 Outcomes Anticoagulant, Antihypertensive or Lipid Lowering drugs NOT prescribed when clinically indicated • Analysis • % of patients with missed prevention opportunities • Logistic regression

  3. What the Researchers Found % Missed opportunities: • Any prevention drug: 54% (9,579/17,680) • Anticoagulants: 52% (1,647/3,194) • Lipid lowering drugs: 49% (7,836/16,028) • Antihypertensives:25% (1,740/7,008) Change over time (2009-2013) • Only anticoagulant drug prescribing improved Predictive patient/ demographic characteristics • Different profile for each drug

  4. What This Means for Clinical Practice Primary stroke prevention is inadequate • Ageing population • Guideline changes • Legal considerations Barriers to prescribing Patient GP Organisational

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