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Vasan Venugopalan Professor

Venugopalan Lab Photons and Transport vvenugop @uci.edu http://www.eng.uci.edu/users/vasan-venugopalan.

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Vasan Venugopalan Professor

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  1. Venugopalan LabPhotons and Transportvvenugop@uci.eduhttp://www.eng.uci.edu/users/vasan-venugopalan • Research Summary: Venugopalan laboratory activities center around the study of photon transport, photo-induced thermal and mechanical transport processes, and their application to non-invasively image, characterize, and/or manipulate biological systems across spatial scales. Our group is highly multi-disciplinary with expertise spanning from applied mathematics, physics, and chemistry on one end to chemical engineering, biomedical engineering, and materials science on the other. Areas of current interest include: • Mathematical and computational analysis of light transport in cells and tissues with applications to thick tissue imaging and non-invasive measurement of tissue structure, composition, and function. • Development of highly-focused laser microbeam technologies for targeted cellular separation, injection, and mechanical stimulation. • Time-resolved microscopy, interferometry, and holography of laser-driven transport processes on nanosecond time-scales. • Research in the Venugopalan lab involves the integration of experiment, modeling, and computational approaches. Potential students are expected to display a high level of motivation, initiative, and interest in contributing to a dynamic, collaborative, inter-disciplinary research environment. • Vasan Venugopalan Professor • B.S. (with honors) Mechanical Engineering, University of California, Berkeley (1988) • S.M., Sc.D., Mechanical Engineering, Massachusetts Institute of Technology (1990, 1994) Nanosecond laser-microbeam cell lysis Key Publications: “Impact of release dynamics of laser-irradiated polymer micropallets on the viability of selected adherent cells”, H. Ma, W Mismar, Y Wang, DW Small, M Ras, NL Allbritton, CE Sims, V Venugopalan. Journal of the Royal Society Interface (2012). “Analysis of single Monte Carlo methods for prediction of reflectance from turbid media”, M Martinelli, AR Gardner, DJ Cuccia, CK Hayakawa, J Spanier, V Venugopalan. Optics Express 19(20):19627–19642, (2011). “Amplitude and phase of tightly focused laser beams in turbid media”, CK Hayakawa, V Venugopalan, VV Krishnamachari, EO Potma, Physical Review Letters103(4):0439039,(2009). “Biophysical response to laser microbeam-induced cell lysis and optoinjection”, Journal of Biophotonics1(1):24-35, (2008). “Laser-induced mixing in microfluidic channels”, Analytical Chemistry79(12):4484-4492, (2007). “Laser microbeam induced cell lysis: Time-resolved imaging and analysis of hydrodynamic effects”, Biophysical Journal91(1):317-329, (2006). Laser based for microfluidic mixing and cell lysis Focused laser beam propagation in turbid media

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