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Digestive System. Part 2 Page 412-417 Practice problems page 420, #1,2,3,4a,5,7,8. Human digestive system. The Stomach. Muscular sac of acid Performs mechanical and chemical digestion Starts the breakdown of proteins. The Stomach. Sphincter : Know the sphincters of the stomach!.
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Digestive System Part 2 Page 412-417 Practice problems page 420, #1,2,3,4a,5,7,8
The Stomach • Muscular sac of acid • Performs mechanical and chemical digestion • Starts the breakdown of proteins
The Stomach • Sphincter: • Know the sphincters of the stomach!
The Stomach • Layer to know: Muscularis • Chyme
The Stomach • Mucosa: another layer to know • What is the function of the mucosa • Gastric juice: what is it and how does the mucosa protect itself from it?
Pepsin • Catalyzes the breakdown of proteins into their amino acid subunits • Originally produced as pepsinogen • Page 411, #5
Mucosa • Due to proximity to strong acid, must be constantly regenerated • Ulcer: • Heliobacter pylori: What role does this bacteri play in the production of ulcers?
Small Intestine • Long (up to 7m), thin (2.5cm) tube • Site of the majority of digestion and absorption
Small Intestine • Know these and what goes on at each! • Duodenum • Jejunum • Ileum
Small Intestine • Pyloric sphincter:
Pancreas • Bicarbonate ions (HCO3-) • Amylase: • Trypsinogen: • Trypsin: • Compare and contrast pepsin/pepsinogen with trypsin/trypsinogen.
Pancreas • Carboxypeptidase and erepsin: • Lipases: • What difficulty do lipases encounter when digesting food?
Liver • Produces bile • Stores it in the gall bladder • Bile emulsifies fats • What is this and why?
Absorption • Once food is broken down into the smallest subunits, it is absorbed by the cells lining the small intestine and passed into the bloodstream • Occurs in the villi and microvilli
Absorption – Surface area • Ridges • Villi • Epithelial cells • Microvilli
Absorption - Transport • How do nutrients get absorbed? • Passive transport: • Diffusion • Osmosis • Facilitated diffusion • Know examples of molecules that get transported by these mechanisms!
Absorption – Active transport • Active transport: • Involves movement of molecules against a concentration gradient