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Change in thrombin generation following edoxaban 60 mg once-daily in healthy subjects. 40. 20. 0. -20. % change from baseline, thrombin peak. -40. -60. -80. -100. 36. 48. 60. 0. 12. 24. 72. Time (hours post-dose). Lip and Agnelli. Eur Heart J. 2014 .
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Change in thrombin generation following edoxaban 60 mg once-daily in healthy subjects 40 20 0 -20 % change from baseline, thrombin peak -40 -60 -80 -100 36 48 60 0 12 24 72 Time (hours post-dose) Lip and Agnelli. Eur Heart J. 2014