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Viruses and Diseases in the Civil War. Miss Sabia. Objectives. Be able to summarize both the lytic and lysogenic cycle. Be able to compare the structure and characteristics of viruses and bacteria. Be able to properly perform a swab technique. The Main Killers. Typhoid Pneumonia Measles
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Viruses and Diseases in the Civil War Miss Sabia
Objectives Be able to summarize both the lytic and lysogenic cycle. Be able to compare the structure and characteristics of viruses and bacteria. Be able to properly perform a swab technique.
The Main Killers Typhoid Pneumonia Measles Tuberculosis malaria
Pathogens Microbes that cause diseases… VIRUSES and BACTERIA
Bacteria Earliest form of life (3 billion years ago) Prokaryotic cells (no organelles, no nucleus) Single celled have a cell wall
Bacteria • 3 shapes: • Cocci (spherical) • Bacilli (rod shaped) • Spirilla (spirals)
Bacteria Use flagella to “swim” or produce thick coats of slime to “slide” around
How Bacteria Infect Give off chemicals called toxins that can make us sick Our body fights off bacterial infections using antibodies
Viruses • Single-celled • Not considered living • Cannot reproduce on their own • They are not made up of cells • They cannot respond to the external environment • Cannot move on their own • Called “particles” or “agents” • About 4,000 different types of viruses
Viruses • Have genetic material (DNA or RNA) enclosed in a capsid • Some viruses have a viral envelope covering their capsid(taken from host cell) • sneaky
How Viruses Infect • Lytic cycle • 1. entry into cell • 2. replicate DNA • 3. make viral proteins • 4. assemble new generation • 5. exit from infected cell—host cell bursts open (lyses) and virus is released into the environment, host cell dies • http://www.youtube.com/watch?v=3DP-MAhr0YY
How Viruses Infect • Lysogenic cycle (sneaky!) • 1. entry into cell • 2. DNA incorporated into host cell’s DNA • 3. host cell copies chromosomes • 4. host cell divides and replicates—all new cells have virus’ DNA incorporated into their own • 5. steps 3-5 from lytic cycle • http://wrate.me.vccs.edu/courses/env108/lesson2_4.htm
Microbiology Lab—Microbes Around Us • Swab Demo:http://www.youtube.com/watch?v=2U6usyE80io • Note: we will not be wetting our swabs in distilled de-ionized water as the video says