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Initial Presentation

Initial Presentation. 43-year-old Caucasian male suffered a seizure 20 days ago. He also had a history of seizure 2 months before, which he did not seek medical attention. He also experience headache, nausea, weakness/numbness of the arm, and poor dental health. Hx.

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Initial Presentation

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  1. Initial Presentation • 43-year-old Caucasian male suffered a seizure 20 days ago. He also had a history of seizure 2 months before, which he did not seek medical attention. • He also experience headache, nausea, weakness/numbness of the arm, and poor dental health.

  2. Hx • Has been diagnosed to have COPD for the past 10 years (currently uses salbutamol to ease the symptoms). • Heavy nicotine addiction (70 pack/year)

  3. Hx Cont’d Family history: • Both parents have heart conditions and mental illnesses.

  4. Hx Cont’d Social/Occupational Hx: • Farmer • Sedentary lifestyle • Still smoking but less

  5. Physical Examinations • BMI: 27 • BP: 123/72 mmHg • HR: 88 beats/min • RR: 15/min • Temp: 38.2 °C

  6. More examination • Purulent gingival drainage and several septic teeth. • Glasgow Coma Scale of 15/15 • Normal PERLLA • Unimpaired cranial nerves and motor-sensor functions • Intact tendon reflexes

  7. DDx • What test should we order? • What organs should we check for?

  8. Smear Test • Positive result of patient’s gingival smear test, indicating the presence of Staphylococcus Haemolyticus

  9. Blood Test • Blood test shows elevated white count, serum C-reactive protein, and procalcitonin • Slightly abnormal blood clot test

  10. Imaging study

  11. Diagnosis ???

  12. Treatment ???

  13. Treatment Cont’d • Surgical removal • Phenytoin • Antibiotics: meropenem, metronidazole, and teicoplanin

  14. Follow up • Patient’s condition has improved dramatically. Blood test shows no inflammation. However, he suffered from another seizure attack 2 days ago.

  15. DDx • What did we miss? Or was it a newly developed condition? • What test should we order?

  16. Bubble Test

  17. Diagnosis ???

  18. Treatment ???

  19. Treatment Cont’d • Blood thinning medication: heparin and warfarin • Closure of PFO via cardiac catheterization

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