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Cytopathology Challenge! Weekly Cases

Cytopathology Challenge! Weekly Cases. October 22th 2007 Pap Smear Special Edition!. 24 year old female. ThinPrep pap Trichomonas Lactobacillus Gonorrhea Bacterial Vaginosis Artifact. 1. 34 year old female. ThinPrep pap Reactive endocervical cells Squamous metaplasia ASCUS LSIL

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Cytopathology Challenge! Weekly Cases

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  1. Cytopathology Challenge! Weekly Cases October 22th 2007 Pap Smear Special Edition!

  2. 24 year old female. ThinPrep pap • Trichomonas • Lactobacillus • Gonorrhea • Bacterial Vaginosis • Artifact 1

  3. 34 year old female. ThinPrep pap • Reactive endocervical cells • Squamous metaplasia • ASCUS • LSIL • HSIL 2

  4. 34 year old female. ThinPrep pap • Endocervical cells • HSIL • Endometrial cells • Squamous metaplasia • Lymphocytes 3

  5. 29 year old female. ThinPrep pap • Squamous metaplasia • Reactive endocervical cells • ASC-US • LSIL • HSIL 4

  6. 24 year old female. ThinPrep pap • Trichomonas • Lactobacillus • Gonorrhea • Bacterial Vaginosis • Artifact 5

  7. 29 year old female. ThinPrep pap • Squamous metaplasia • Reactive endocervical cells • ASC-US • LSIL • HSIL 6

  8. 29 year old female. ThinPrep pap • Squamous metaplasia • Reactive endocervical cells • ASC-US • LSIL • HSIL 7

  9. 29 year old female. ThinPrep pap • Reactive • Endocervical cells • ASC-US • LSIL • HSIL 8

  10. 34 year old female. ThinPrep pap A. Squamous metaplasia B. Reactive endocervical cells C. ASC-US D. LSIL E. HSIL 9

  11. 34 year old female. ThinPrep pap • Contaminant from a BAL • HSIL • Endometrial cells • Adenocarcinoma • Tubal metaplasia 10

  12. Answers • D Bacterial Vaginosis • Clue cells with cocci on them • D LSIL • Koilocytes! • C Endocervical cells • Honeycomb, regular, not dysplastic • E HSIL • High NC ratio, irregular nuclei • B Lactobacillus • Rods on the cells • D LSIL • Koilocytes again! • A Squamous Metaplasia • Can look like HSIL, but nuclei not so big and still regular in contour. • A Reactive • See the trichomonas hiding in there…… • E. HSIL • High NC ratio, irregular nuclei • E Tubal metaplasia • Ciliated cells in a pap smear can be metaplastic ciliated metaplasia.

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