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Background for LVAD papers. Topics. Heart anatomy and function (Ashley) Heart failure (Kelsey) Ventricular assist devices (Julianne) NY Heart Association Functional Class (Philicia) MN Living with HF Questionnaire (Suzy). Heart anatomy and function. 1. 7. 6. 12. 9. 8. 2. 5. 11. 10.
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Topics • Heart anatomy and function (Ashley) • Heart failure (Kelsey) • Ventricular assist devices (Julianne) • NY Heart Association Functional Class (Philicia) • MN Living with HF Questionnaire (Suzy)
Heart anatomy and function 1 7 6 12 9 8 2 5 11 10 3 4 1
Heart anatomy and function – helpful websites • http://www.gwc.maricopa.edu/class/bio202/Cardiovascular/models/hartint0.htm • http://www.vhlab.umn.edu/atlas/index.shtml
LVAD – Left Ventricular Assist Device Fig 1: Diagram of ThoratecHeartMate II in relation to heart How did we get here? Why? Heart failure 1 million hospital discharges Scarcity of organ donors 2200 transplants/ year Bridge to Transplant or Destination Therapy Benefits of Destination Therapy: Survival benefit in end stage heart failure 2 year survival – 77% vs. 8-10% with medications Symptomatic Drawbacks (Complications): Gastro-intestinal bleeding (22%) Stroke (8%) Infection (30%) Major/ Sepsis (17%) Minor (13%) Fig 2: Jarvik 7: Heart Replacement Device Fig 3: Thoratec HeartMate XVE
Resources http://www.heartfailure.org/eng_site/whats_new_heartmate_ii.asp http://www.cpmc.org/advanced/heart/advances/hearthope.html http://www.hearthealthywomen.org/treatment-and-recovery/treatment-and-recovery/lvad.html Badiwala, M.V.; Rao, V. “Left ventricular device as destination therapy: are we there yet?” Current Opinion in Cardiology 2009; 24(2): 184–189. Rose, E. A.; Gelijns, A.C.; Moskowitz, A.J, et. al. “Long-Term Use of a Left Ventricular Assist Device for End-Stage Heart Failure” N Engl J Med 2001; 345:1435-1443
Assessments of heart failure NY Heart Association Functional Class MN Living with HF Questionnaire