1 / 16

Cathleen M. Crudden,* Mutyala Sateesh, and Roxanne Lewis J. Am. Chem. Soc. 2005, 127, 10045

Mercaptopropyl-Modified Mesoporous Silica: A Remarkable Support for the Preparation of a Reusable, Heterogeneous Palladium Catalyst for Coupling Reactions. Cathleen M. Crudden,* Mutyala Sateesh, and Roxanne Lewis J. Am. Chem. Soc. 2005, 127, 10045. Palladium-Catalyzed Reactions.

eadoin
Download Presentation

Cathleen M. Crudden,* Mutyala Sateesh, and Roxanne Lewis J. Am. Chem. Soc. 2005, 127, 10045

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Mercaptopropyl-Modified Mesoporous Silica: A Remarkable Support for the Preparation of a Reusable, Heterogeneous Palladium Catalyst for Coupling Reactions Cathleen M. Crudden,* Mutyala Sateesh, and Roxanne Lewis J. Am. Chem. Soc. 2005, 127, 10045

  2. Palladium-Catalyzed Reactions

  3. Z=COOR, Ph X=Cl, Br, I Suzuki-Reaction X=Cl, Br, I Heck Reaction

  4. www.bgu.ac.il/mesoporous/ html/kinetics.htm

  5. 為何使用SBA-15作為載體 • 具多孔性 • 高表面積 • 表面的silanol密度高，有利(CH3O)3Si(CH2)3SH 與silica表面進行縮合反應

  6. Pd(OAc)2 in THF Treated with Various Scavengers

  7. Scavenging of Pd with SBA-15-SH and SiO2-SH

  8. Suzuki-Miyaura Couplings with SBA-SH-Pd

  9. Substrate Scope for the Suzuki-Miyaura Coupling

  10. Reusability of the Catalyst in the Suzuki-Miyaura Reaction

  11. SBA-15-Modified Pd Catalysts for the Mizoroki-Heck Reaction

  12. Hot Filtration Test

  13. Three-Phase Test in the Suzuki-Miyaura Reaction

  14. Conclusions • Thiol-functionalized mesoporous silicates are efficient Pd scavengers and this materials have high ability of catalysis for Heck and Suzuki reaction. • Several heterogeneity tests were indicate that the majority of the catalysis (>95%) occurs on the support via a truly heterogeneous catalyst.

More Related