Chemotherapeutic Drug Administration

1. Chemotherapeutic Drug Administration Prepared By : Miss. Sana’a AL-Sulami Teacher Assistant

2. Outlines : • Definition of Chemotherapeutic Drug Administration • Administration of Chemotherapeutic Agents • Dosage of chemotherapeutic administration • Equipment of chemotherapeutic drug administration • Implementation of administration chemotherapeutic drugs.

3. Chemotherapeutic Drug Administration : • Administration of chemotherapeutic drugs requires skills in additional to those used when giving other drugs . • For example some drugs require special equipment or must be given through unusual route.

4. Chemotherapeutic Drug Administration : • Others drugs need protection from the light • specially trained nurses and physicians should give chemotherapeutic drugs.

5. Administration of Chemotherapeutic Agents • Chemotherapeutic agents may be administered in the hospital, clinic, or home setting by topical, oral, intravenous, intramuscular, subcutaneous, arterial, intracavitary. • The administration route usually depends on the type of agent, the required dose, and the type, location, and extent of tumor being treated.

6. DOSAGE: • Dosage of antineoplastic agents is based primarily on the • patient’s total body surface area • previous response to chemotherapy or radiation therapy • major organ function.

7. Complication of Chemotherapeutic Drugs: • Nausea and vomiting • Intestinal irritation • Stomatitis • Hearing loss • Anemia • Alopecia

8. Complication of Chemotherapeutic Drugs: • Diarhea • constipation • Inflammation, ulceration, necrosis and loss of vein patency.

9. Equipment : • 1-Prescribed drug • 2-Gloves • 3-Aluminum foil • 4-Normal saline solution • 5-Syringe and needles • 6-Normal pump or controller

10. Implementation: • Assess the patient's physical condition, and review his medical history • Make sure you understand what chemotherapeutic agent needs to be given and by what route, and provide the necessary teaching and support to the patient and his family

11. Implementation: • Confirm the patient's identity according to your facility policy • Determine the best site to administer the drug, When selecting the site, consider drug compatibilities, frequency of administration

12. Implementation: • Evaluate your patient's condition, the result of recent laboratory studies . • Determine whether the patient has received chemotherapy before ,and note the severity of any adverse effects. • Check his drug history for medications that may interfere with chemotherapy. Talk with the physician or pharmacist before you give it.

13. Implementation: • Check the patient's chart for complete chemotherapy protocol order, including the patient's name and dosage, and route ,rate and frequency of administration • Check to see whether the physician has ordered an antiemetic, fluids , a diuretic, or electrolyte supplements to be given before , during , or after chemotherapy administration.

14. Implementation: • Evaluate the patient's and his family's understanding of chemotherapy, and make sure the patient or a responsible family member has signed the consent form. • Put on gloves. Keep them on through all stages of handling the drug including preparation, I.V. tubing, and administration.

15. Implementation: • Before administering the drug avoid giving chemotherapeutic drugs through an existing I.V. line. • To identify an administration site, examine the patient's veins starting with his hands and proceeding to his forearm. • When an appropriate line is in place, infuse 10 to 20 ml of normal saline solution to test vein patency .

16. Implementation: • Never test vein patency with a chemotherapeutic drug. Next, administer the drug as appropriate. • Closely monitor the patient for signs of hypersensitivity reaction. • After infusion of the medication, infuse 20 ml of normal saline solution. Do this between administrations of different chemotherapeutic drugs and before discontinuing the I.V. line.

17. Implementation: • Dispose of used equipment in properly container. • Wash your hands thoroughly with soap and warm water after giving any chemotherapeutic drug

18. Documentation: • Location & description of the I.V site before treatment • Record the drug & dosage administration • Sequence of drug administration • Needle type and the size used • Amount & type of flushing solution

19. Documentation: • Document any adverse reaction • Patient’s tolerance of treatment. • Topics discussed with the patient and his family.