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Jennifer Ross Department of Physics, University of Massachusetts Amherst. Which of these movies shows activites taking place inside a cell? The answer might surprise you!. Movie 1. Movie 2. Movie 3. Movie 4. Jennifer Ross Department of Physics, University of Massachusetts Amherst.
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Jennifer Ross Department of Physics, University of Massachusetts Amherst Which of these movies shows activites taking place inside a cell? The answer might surprise you! Movie 1 Movie 2 Movie 3 Movie 4
Jennifer Ross Department of Physics, University of Massachusetts Amherst The answers In a cell Not in a cell Not in a cell Microtubules (red) with severing enzymes (green) reconstituted in vitro with purified proteins. (J.D. Diaz-Valencia, M.M. Morelli, M. Bailey, D. Zhang, D.J. Sharp, and J.L. Ross, “Drosophila Katanin-60 Depolymerizes and Severs at Microtubule Defects,” Biophysical Journal, 100, 2440-2449 (2011).) Microtubules inside an S2 cell (D. Zhang, K.D. Grode, S.F. Stewman, J.D. Diaz-Valencia, E. Liebling, U. Rath, T. Riera, J.D. Currie, D.W. Buster, A.B. Asenjo, H.J. Sosa, J.L. Ross, A. Ma, S.L. Rogers and D.J. Sharp “Drosophila katanin is a microtubule depolymerase that regulates cortical-microtubule plus-end interactions and cell migration,” Nature Cell Biology, 13, 361-369 (2011).) Microtubule bundled with MAP65 crosslinking proteins being propselled by kinesin-1 motor proteins using purified proteins. (J. Pringle, A. Muthukumar, A. Tan, L. Crankshaw, L. Conway, J.L. Ross, “Microtubule Organization by Kinesin Motors and the Microtubule Crosslinking Protein, MAP65,” in press at Journal of Physics: Condensed Matter, Special issue: Physics of Protein Motility, (2013).)