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Young S. Kim & Padma Maruvada Nutritional Science & Cancer Biomarkers Research Group

Frontiers in Metabolomics for Cancer Research. Young S. Kim & Padma Maruvada Nutritional Science & Cancer Biomarkers Research Group Division of Cancer Prevention. Background. Application of high throughput technologies to biological questions in the post-genomic era

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Young S. Kim & Padma Maruvada Nutritional Science & Cancer Biomarkers Research Group

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  1. Frontiers in Metabolomics for Cancer Research Young S. Kim & Padma Maruvada Nutritional Science & Cancer Biomarkers Research Group Division of Cancer Prevention

  2. Background • Application of high throughput technologies to biological questions in the post-genomic era • NIH Roadmap initiatives promoting technology development in metabolomic platforms • Metabolomic approaches to cancer research

  3. Questions…. • Can tumor specific metabolic alterations reflect in body fluids? • What are the factors that would influence metabolic fluxes? • What molecules do you include in the definition? • What are the appropriate metabolomics technologies for cancer research? • How do we get some meaningful information? • What are the needed sensitivity, reproducibility, and dynamic range for their clinical utility?

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