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PXI-Based Magnetic Imaging System for Diagnosing Infant Brain Activity

PXI-Based Magnetic Imaging System for Diagnosing Infant Brain Activity. Tristan Technologies, Inc., San Diego, CA . babySQUID ® Neonatal Biomagnetometer. S uperconducting QU antum I nterference D evice. Competing Methodologies. Adult Magnetoencephalography (MEG)

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PXI-Based Magnetic Imaging System for Diagnosing Infant Brain Activity

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  1. PXI-Based Magnetic Imaging System for Diagnosing Infant Brain Activity Tristan Technologies, Inc., San Diego, CA

  2. babySQUID® Neonatal Biomagnetometer Superconducting QUantum Interference Device

  3. Competing Methodologies • Adult Magnetoencephalography (MEG) • Multi-million dollar systems requiring large magnetically shielded rooms • Poorer spatial resolution • fMRI • Not truly “functional” • Poor time resolution • Requires infants to be sedated • Contrast agents often needed • PET • Requires administration of radioisotopes may not be possible with infants • Poor time resolution • EEG • Lack of unique source location • Electrodes must be placed on skull (time consuming)

  4. A new way to evaluate neurological impairments of infants by magnetic mapping • 100% non-invasive MEG (MagnetoEncephaloGraphy) • Directly measures neural activity • Portable – goes from hospital elevator to bedside • Needs NO shielded room

  5. Data Acquisition System • 24 bit resolution • 10 kSample/sec sampling rate, simultaneous • 88 data channels, expandable • Both hardware and software buffered • Fiber optic data link • Multi-PXI configuration currently being developed

  6. babySQUID® User Interface

  7. babySQUID® User Interface • Sensor Positioning • Incoming Data • Live, Playback, & Simulation • Filters & Filter editors • Monitoring Displays • Data Averaging • Artifact Rejection • Filters & Filter editors • Monitoring Displays

  8. babySQUID® User Interface • Sensor Positioning • Incoming Data • Live, Playback, & Simulation • Filters & Filter editors • Monitoring Displays • Data Averaging • Artifact Rejection • Filters & Filter editors • Monitoring Displays

  9. RealTime Head Tracking Zoom Pan Rotate

  10. RealTime Head Tracking Zoom Pan Rotate

  11. RealTime Head Tracking Zoom Pan Rotate

  12. RealTime Head Tracking Zoom Pan Rotate

  13. RealTime Head Tracking Zoom Pan Rotate

  14. RealTime Head Tracking Zoom Pan Rotate

  15. RealTime Head Tracking Zoom Pan Rotate

  16. RealTime Head Tracking Zoom Pan Rotate

  17. RealTime Head Tracking Zoom Pan Rotate

  18. Simulated Field Projected onto Skin Surface

  19. Simulated Field Projected onto Skin Surface

  20. Simulated Field Projected onto Skin Surface

  21. Simulated Field Projected onto Skin Surface

  22. babySQUID® User Interface • Sensor Positioning • Incoming Data • Live, Playback, & Simulation • Filters & Filter editors • Monitoring Displays • Data Averaging • Artifact Rejection • Filters & Filter editors • Monitoring Displays

  23. babySQUID® User Interface • Sensor Positioning • Incoming Data • Live, Playback, & Simulation • Filters & Filter editors • Monitoring Displays • Data Averaging • Artifact Rejection • Filters & Filter editors • Monitoring Displays

  24. Averaged Data Incoming Data

  25. Averaged Data Incoming Data

  26. Averaged Data Incoming Data

  27. Averaged Data Incoming Data

  28. Averaged Data Incoming Data

  29. Averaged Data Incoming Data

  30. Averaged Data Incoming Data

  31. Averaged Data Incoming Data

  32. Averaged Data Incoming Data

  33. Averaged Data Incoming Data

  34. Averaged Data Incoming Data

  35. Averaged Data Incoming Data

  36. babySQUID® User Interface • Sensor Positioning • Incoming Data • Live, Playback, & Simulation • Filters & Filter editors • Monitoring Displays • Data Averaging • Artifact Rejection • Filters & Filter editors • Monitoring Displays

  37. babySQUID® User Interface • Sensor Positioning • Incoming Data • Live, Playback, & Simulation • Filters & Filter editors • Monitoring Displays • Data Averaging • Artifact Rejection • Filters & Filter editors • Monitoring Displays

  38. Live • PlayBack • Simulation Selectable Data Source

  39. Just turn the knob!

  40. babySQUID® User Interface • Sensor Positioning • Incoming Data • Live, Playback, & Simulation • Filters & Filter editors • Monitoring Displays • Data Averaging • Artifact Rejection • Filters & Filter editors • Monitoring Displays

  41. babySQUID® User Interface • Sensor Positioning • Incoming Data • Live, Playback, & Simulation • Filters & Filter editors • Monitoring Displays • Data Averaging • Artifact Rejection • Filters & Filter editors • Monitoring Displays

  42. Many Data Displays Sub-panels allow dynamic loading • Scope • Correlation • Intensity • Linear • Butterfly • Time-Freq • Surface • User-Defined

  43. babySQUID® User Interface • Sensor Positioning • Incoming Data • Live, Playback, & Simulation • Filters & Filter editors • Monitoring Displays • Data Averaging • Artifact Rejection • Filters & Filter editors • Monitoring Displays

  44. babySQUID® User Interface • Sensor Positioning • Incoming Data • Live, Playback, & Simulation • Filters & Filter editors • Monitoring Displays • Data Averaging • Artifact Rejection • Filters & Filter editors • Monitoring Displays

  45. Multiple Stackable Filters Sub-panels allow dynamic loading • FIR/IIR filters • Decimation • Spectrogram • Wavelet • Ref. Chan. Corr. • User-defined

  46. ReferenceChannelCorrelation Removes distant noise sources

  47. SpectrogramMask Frequency vs Time Threshold Mask

  48. SpectrogramMask Frequency vs Time Threshold Mask

  49. SpectrogramMask Frequency vs Time Threshold Mask

  50. SpectrogramMask Frequency vs Time Threshold Mask

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