1 / 10

Volumetric Studies

Volumetric Studies. Current Technology. Image Acquisition: 1.5 Tesla GE scanner, 1 coronal SPGR, 1 axial Double Echo PD and T2w image. Rigid Registration: Mutual Information Alignment. Brain Segmentation: Expectation Minimization Segmentation in 4 tissue classes (White, Gray, CSF and Face).

elom
Download Presentation

Volumetric Studies

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Volumetric Studies

  2. Current Technology • Image Acquisition: • 1.5 Tesla GE scanner, 1 coronal SPGR, 1 axial Double Echo PD and T2w image. • Rigid Registration: • Mutual Information Alignment. • Brain Segmentation: • Expectation Minimization Segmentation in 4 tissue classes (White, Gray, CSF and Face). • Manual Segmentation of Regions Of Interests. • Statistical Analysis of the ROIs’ Volume.

  3. Brain Segmentation W. Wells

  4. Posterior Superior Temporal Gyrus (STG)Red = Left, Green= Right• Amygdala. Yellow = Left, Light Blue = Right• Hippocampus (Hipp.). Orange = Left, Dark Blue = Right • Parahippocampal Gyrus (PHG). Dark Pink = Left, Purple = Right L. Post. STG L. STG Hipp. PHG L. Amygdala. L. Ant. STG L. Post. STG L. Hipp. Hirayasu et al.

  5. Volumetric Studies Findings • Lateral Ventricles & CSF Enlargement. • Parietal Volume Reduction. • Temporal Lobe Volume Reductions • Amygdala-Hippocampal Complex, Parahippocampal Gyrus, & Superior Temporal Gyrus. • Prefrontal Volume Reduction. • Basal Ganglia (Caudate, Putamen, Globus Pallidus) increases and decreases.

  6. Volumetric Studies

  7. Shape: Global Measures J. Levitt and C.F. Westin

  8. Shape: Surface Based Analysis H.J. Park and J. Levitt

  9. Shape: Medial Representations J. Levitt and S. Bouix

  10. Technical Challenges • Image Quality and Acquisition Sequences. • Multi Channel Atlas Based Segmentation. • Multi Channel Image Registration. • Model Based Segmentation. • Shape Analysis. • Cortical Thickness.

More Related