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Final Session SEARCH MULTIPLE RESOURCES Knowledge Assessment. Merck Manual of Diagnosis and Therapy Medline (PubMed) Cochrane Library Clinical Evidence Science–Technology–Medicine + Cited Reference Search + Journal Impact Factor. Web of Knowledge.
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Final SessionSEARCH MULTIPLE RESOURCES Knowledge Assessment Merck Manual of Diagnosis and Therapy Medline (PubMed) Cochrane Library Clinical Evidence Science–Technology–Medicine + Cited Reference Search + Journal Impact Factor Web of Knowledge
Searching –Finding - Appraising Clinical Question for Today: Enuresis (Bedwetting) in school children: Treatment options
CLINICAL QUESTION FOR TODAY • Case • 11-year old boy with enuresis (bedwetting) • Urinary tract infections excluded; • Frustrated with his health problem • Possible treatment options: 1. Drug therapy (desmopressin) 2. Enuresis alarm 3. Combination of desmopressin + alarm? Adapated from:BMJLearning http://http://learning.bmj.com
BACKGROUND INFORMATION • Definition of enuresis (bedwetting) • Merck Manual of Diagnosis and Therapy http://www.merckmanual.com Search: enuresis +desmopressin +alarms
Enuresis – what it is about Primary nocturnal enuresis • Failure to have developed bedtime bladder control • Usually caused by slow maturation of the nervesthat supply the bladder • The child fails to awaken appropriately when the bladder fills and needs emptying. • affects 30% of children at age 4, • 10% at age 6, • 3% at age 12, • and 1% at age 18. • It is more common in boys, • Seems to be familial, • Sometimes associated with sleep disorders.
FOREGROUND QUESTIONTerminology • enuresis; enuretic; bedwet; bedwetting • drug(s); desmopressin; • alarm(s)
PubMed Search Strategy Suggestions Step 1 enure* OR bedwet* Limits: Title Step 2 desmopressin* OR drug* OR alarm* Limits: Title Step 3 Combine searches #1 AND#2 Step 4 Limits: Ages: Child 6-12
PubMed Search Results (2) • All: 224 • Reviews: 25 • 8 Cochrane Reviews of randomized controlled trials
Professional Databases with Critically Appraised Topics Clinical Evidence http://www.clinicalevidence.com (fee) • Systematic reviews • Question(s) • Option(s) • Grades of evidence • Beneficial • Likely beneficial • Trade off between benefit and harm • Unknown effectiveness • Unlikely beneficial • Etc.
CRITICAL APPRAISAL„Bibliometric Criteria“ Multidisciplinary database WEB OF KNOWLEDGE • Which journal was it written in? • „Impact Factor“ = journal quality • Additional resources • Journal Citation Reports (part of WoS) • Who wrote the article? • Was the article citedby other articles? • Web of Science (part of WoK) • Science Citation Index (tool)
WEB OF SCIENCEMultidisciplinary Database Palacky University Authorized Access at: http://isiknowledge.com Search Cited Reference Search Journal Citation Reports
Which journal was it published in ?Journal Impact Factor http://isiknowledge.com Additional Resources – Journal Citation Reports • Cited author(s): Naitoh Y et al. • Article title:Combination therapy with alarm and drugs for monosymptomatic nocturnal enuresis not superior to alarm monotherapy.. • Cited work:Urology • Publication Year:2005 • Volume/Issue: 660/3 • Pagination: 632-635.
UrologyImpact Factor Calculation Calculation • Number of articles published in: 2004 = 584 + 2003 = 599 Sum:1183 • Number of cites in 2005to articles published in: 2004 = 897 + 2003 = 1634 Sum: 2531 Cites to articles2531 Number of articles 1183 = 2.139 Impact factor
Was article cited by other articles? Science Citation Index (SCI) http://isiknowledge.com CITED REFERENCE SEARCH • Cited author(s):Naitoh Y et al. • Article title:Combination therapy with alarm and drugs for monosymptomatic nocturnal enuresis not superior to alarm monotherapy.. • Cited work:Urology • Publication Year:2005 • Volume/Issue:660/3 • Pagination: 632-635.
MORE ABOUT BIBLIOMETRICS • Introduced in 1960s …„application of mathematical and statistical methods to books and other media of communication“
INSTITUTE FOR SCIENTIFIC INFORMATION & ITS FOUNDER • Eugene Garfield. Ph.D. www.garfield.library.upenn.edu • 1951career in scientific communication and information science • 1960founded ISI • 2001-President, The Scientist.
SCIENCE CITATION INDEX (SCI) • has become the most generally accepted source of bibliometrics. • Citations became a widely used measure of the impact of scientific publications as • signposts left behind after information has been utilized.
CRITICAL APPRAISALIn general Technique, skill • Increasing effectiveness of your reading • Excluding poorly designed studies • Helping decide • which articles could influence your daily work • which are unsuitable.