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Scenario 1

Results: Author Estimate -Medium Risk. No of Risk Factors-2. Respondent Risk Estimate 2/1,000 patients per year. Proportion favoring PPI - 0.71. Scenario 1. 30 year old male Metal mitral valve replacement Lifelong warfarin Nimesulide following a wrist fracture

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Scenario 1

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  1. Results: Author Estimate -Medium Risk. No of Risk Factors-2. Respondent Risk Estimate 2/1,000 patients per year. Proportion favoring PPI - 0.71 Scenario 1 • 30 year old male • Metal mitral valve replacement • Lifelong warfarin • Nimesulide following a wrist fracture • Estimate the annual risk of GI bleed • ? PPI prescription

  2. Results: Author Estimate -Medium Risk. No of Risk Factors-2. Respondent Risk Estimate 2/1,000 patients per year. Proportion favoring PPI - 0.81 Scenario 2 • 50 year old female with RA • Uses NSAIDs occasionally • Coronary artery stenting • Aspirin and clopidogrel • Estimate the annual risk of GI bleed • ? PPI prescription

  3. Results: Author Estimate -High Risk. No of Risk Factors-4. Respondent Risk Estimate 10/1,000 patients per year. Proportion favoring PPI - 0.76 Scenario 3 • 80 year old female • IHD. Atrial fibrillation • Aspirin, clopidogrel, warfarin • Estimate the annual risk of GI bleed • ? PPI prescription

  4. Results: Author Estimate -High Risk. No of Risk Factors-2. Respondent Risk Estimate 10/1,000 patients per year. Proportion favoring PPI - 0.8 Scenario 4 • 60 year old male • Low back pain. Rx with NSAIDs • Triple therapy for DU aged 51 • Estimate the annual risk of GI bleed • ? PPI prescription

  5. Results: Author Estimate -Low Risk. No of Risk Factors-1. Respondent Risk Estimate 1/1,000 patients per year. Proportion favoring PPI - 0.1 Scenario 5 • 40 year old female • DM and hyperlipidaemia. F Hx of IHD • Taking daily low dose aspirin • Estimate the annual risk of GI bleed • ? PPI prescription

  6. Results: Author Estimate -High Risk. No of Risk Factors-3. Respondent Risk Estimate 2/1,000 patients per year. Proportion favoring PPI - 0.52 Scenario 6 • 80 year old male • IHD and CCF • Aspirin and clopidogrel • Estimate the annual risk of GI bleed • ? PPI prescription

  7. Results: Author Estimate - Low Risk. No of Risk Factors-2. Respondent Risk Estimate 1/1,000 patients per year. Proportion favoring PPI - 0.58 Scenario 7 • 50 year old male • COPD • Taking aspirin and prednisolone • Estimate the annual risk of GI bleed • ? PPI prescription

  8. Results: Author Estimate -High Risk. No of Risk Factors-3. Respondent Risk Estimate 2/1,000 patients per year. Proportion favoring PPI - 0.76 Scenario 8 • 70 year old female with hip fracture • TIA in past – low dose aspirin • Now taking NSAIDs for hip pain • Estimate the annual risk of GI bleed • ? PPI prescription

  9. Results: Author Estimate - Low Risk. No of Risk Factors-2. Respondent Risk Estimate 2/1,000 patients per year. Proportion favoring PPI - 0.59 Scenario 9 • 30 year old female • Lifelong warfarin for recurrent DVT • Commenced on prednisolone for sarcoidosis • Estimate the annual risk of GI bleed • ? PPI prescription

  10. Results: Author Estimate -Medium Risk. No of Risk Factors-2. Respondent Risk Estimate 2/1,000 patients per year. Proportion favoring PPI - 0.80 Scenario 10 • 60 year old male • IHD, taking clopidogrel • Rx NSAIDs for osteoarthritis • Estimate the annual risk of GI bleed • ? PPI prescription

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