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AP Biology. During development an organisms cells differentiate from Stem cells Stem cell – any unspecialized cell that can produce, during a single division one identical daughter cell and one more specialized daughter cell This occurs via structural and functional divergence of cells.
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During development an organisms cells differentiate from Stem cells • Stem cell – any unspecialized cell that can produce, during a single division one identical daughter cell and one more specialized daughter cell • This occurs via structural and functional divergence of cells Cell Specialization
Molecular level (chemicals) • Cell • Tissue • Organ • Organ system • Organism Cellular organization
Negative – Reduces frequency, regulates physiological processes back to a target set point (long term) • Positive – Increase frequency or amplify processes (short term) Positive and Negative feedback
Regulator Vs Conformer Temp. regulation
To become attractive plants produce fruit, this makes them desirable so animals will take and carry off their seeds. Plants communicate via ethylene – a gas
Lactation in mammals – When baby drinks milk, hormones prolactin and oxytocin are released, this causes milk to be released and produced. • Child birth – pressure on cervix causes contractions. Contractions cause more pressure • Blood clotting – vascular spasms Decrease blood flow, plug formation, coagulation Other Positives
Some changes to homeostasis are regulated and many are controlled by hormones. • Examples: • Women’s menstrual cycle • Circadian rhythm (changes that occur every 24 hours) • Acclimation- gradual process in which animal adjusts to external environment Alteration of feedback
Thermoregulation – process by which animals maintain an internal temperature • Endothermic – warmed by heat they generate via metabolism • Ectothermic – gain heat via external sources Maintaining homeostasis physiological
Balancing Heat Loss and gain • Integumentary system • Insulation • Circulatory adaptations • Cooling via evaporative heat loss Maintaining homeostasis
Increases blood flow to help keep warm • Decreases blood flow to help keep cool Maintaining homeostasis
Countercurrent exchange- exchange of heat via fluids or between fluids that are moving in the opposite direction Maintaining homeostasis
Maximize sunlight absorption • Postures • Huddling together • Torpor • Hibernation Maintaining homeostasis behavioral
Homeostatic disruptions are anything that affects the individual or the environment in which the individual lives in • Can be: • Molecular level • Ecosystem level Disruptions In Homeostasis
Problem in feedback loops • Can be • Type I (juvenile or child onset) • Type II • Both cases cells are not communicating in the feedback loop dealing with blood sugar Diabetes
Diabetes Insulin Blood glucose glucagon Alteration of feedback
Dehydration: Molecular disruption
Invasive species: A species, often introduced by humans, that takes hold outside its native range Ecosystem disruptions
Response: Anything an organism does as a result of its surroundings • Can be: • Behavioral • Physiological Form and Function
Occurs as a population or a group of organisms • Examples: • Hibernation • Migration Can be learned or inherited Behavioral Responses
Changes within the organism • Examples: • Shivering • Sweating- evaporative cooling Physiological responses
Plants and animals defend themselves from pathogens • Pathogens- invaders • 2 major forms of defense: • Nonspecific • Specific Physiological-Defense
Kills anything that invades (skin, saliva, normal bacteria, swelling, inflammation etc.) • Plants sense pathogens using Hypersensitive Responses Nonspecific
R gene in chromosomes – senses invading proteins • R gene will initiate a hypersensitive response • Oxidative burst – apoptosis • Proteins sent to adjacent cells will change cell wall • Memory does not occur Nonspecific - hypersensitive
Specific responses identify pathogens and attack them • Occurs in 2 forms: • Humoral – occurs in humor/liquid/blood/lymphatic • Cell mediated – target infected cells Specific
Humoral responses are governed by B cells • B cells produce memory Antibodies • Antibodies target invaders • Invaders are called antigens - Humoral
Antibodies have antigen-binding sites • Antigen- is an antibody generating organism • fungus, bacteria, virus etc. Humoral
Antigen present – invader • Antigen is engulfed (eaten) by a WBC or macrophage • WBC will take some of the antigen and put it on the surface of its cell (Antigen Presenting Cell) • Helper T cells- recognize the shape of the antigen • Helper T cells- activate B cells to make antibodies a. plasma B – makes antibodies b. memory B 6. B cells invade antigens Humoral
This response targets infected cells • Called cytotoxic T cells – kills own cells that are infected Cell-mediated
How does this happen? Physiological- Development
Seed Germination – • When planting seeds it needs 2 things to survive (water and temperature) must be in correct combination • Germinating cells will appear different Physiological
First step in development is cellular differentiation • DNA will express specific proteins that determine each tissue – called tissue specific proteins • Cells will eventually specialize Physiological
Zygote makes a copies of itself • Forms a sphere (blastula) • Blastula folds in on itself (gastrula) forms ectoderm, mesoderm and endoderm • Transcription factors give off proteins that help to determine what should happen Physiological - differentiation
Step 2 is embryonic induction: • Cells induce other cells to become like them, give off proteins • Cells induce adjacent cells next to it Physiological - induction
Just as important as cell growth • Hid, Grim, Reaper Genes • These genes are needed between fingers and toes etc. • microRNA genes – control hid, grim, reaper genes Physiological – cell death
How do cells “know” the body plan of organisms? • Homeotic genes – are a series of genes that “tell” drosophila where to put the organs/appendages etc. • Famous ones are HOX genes We learned from the mutants Ultrabithroax will duplicate the thorax Antp- one leg will grow of the head Series of genes that codes for body plan Physiological- Homeotic genes
When traveling – especially across time zones jet-lag occurs Timing and control
Phototrophism – how plants grow toward or away from light Toward light + Away from light – Hormone: Auxin Timing and control - plants
Photoperiodism – how plants respond to changing amounts of light during the season Phytochrome – light receptor- when absorb light, will change shape to let plant know what time of day and season it is (regulates cellular activities) Timing and control - plants