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Laboratory Animal Medicine. A Key to A Very Bright Future. Name of LAM Vet presenting. Raise your hand if…. You have ever been vaccinated You have ever taken a medication You have ever had surgery/hospital stay You have ever donated or received blood
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Laboratory Animal Medicine A Key to A Very Bright Future Name of LAM Vet presenting
Raise your hand if…. • You have ever been vaccinated • You have ever taken a medication • You have ever had surgery/hospital stay • You have ever donated or received blood • You know someone who has had diabetes, cancer or other diseases
Many current medical treatments depend on animal research. • Vaccines against polio, measles and smallpox “Iron lung used for polio victims, 1956”
Open-heart surgery, coronary bypass, heart valve replacement • Diabetes therapies
...These treatments benefit not only people, but animals too!
Pookie: Living with diabetes Maggie: Breast cancer survivor Lucy: After her kidney transplant Buddy: After his heart surgery
But a lot of misinformation has been spread about animal research. • Some people do not realize the many benefits of animal research to both people and animals. • People do not always know that animals are treated humanely and with great respect.
Despite these misconceptions, 2/3 to 3/4 of Americans support the need for animal research. • 6
“One world, one health, one medicine” • While new diseases lie ahead for people and animals, animal research can help us investigate and treat these.
Diverse career opportunities exist in laboratory animal medicine (LAM). • Clinical veterinary medicine • Administration • Research • Teaching and training • Pathology • Regulatory oversight
Clinical LAM vets provide health care for a variety of species. • They may also: • Review research protocols to ensure animal welfare • Consult with scientists about model development • Provide technical support for research (perform ultrasound exams or surgeries) • No 2 days are alike!
Administration • Manage budget and staffing issues • May write grants to improve the program or request equipment • Liaison to senior management to ensure support for optimal animal program
Research • Veterinarians may head or contribute to research projects • Independent or collaborative research • Tremendous diversity of research • Infectious disease, physiology, biology, reproduction, surgery, cancer biology, pharmaceutics, neuroscience, biomedical instrumentation, toxicology…
Teaching & Training • LAM vets teach in veterinary schools, veterinary technician schools, graduate programs. • Veterinarians can serve as trainers for other veterinary residents, graduate students, research staff, animal care staff. • A well-developed training program is an essential part of a good lab animal program.
Pathology • Pathologists with laboratory animal expertise are in great demand! • They are required to help diagnose rodent strain abnormalities, drug side effects, and diseases in individual research animals.
Regulatory Oversight • Institutional Animal Care and Use Committee (IACUC) is mandated by USDA regulations • Must include a LAM veterinarian • Review all animal use protocols, and animal facilities • Investigate animal concerns
Alternatives (3Rs) = Reduce, Refine, Replace • Reduce animal numbers • Better statistics, less redundancy • Refinement of animal models • Less invasive procedures, better analgesics and anesthetics • Replacement of animal models • Cell culture, computer modeling
Environmental Enrichment Animals are also provided enrichment in the form of exercise, toys, music, group housing, videos and other food treats. 19
What animal species will I work with? • Depends on type of program • ~95% of research animals are rats/mice. • Rodents, genetically-engineered. • ~5% other species • Domestic species (dogs, ferrets, pigs). • Nonhuman primates • Exotics – woodchucks, bats, fish, amphibians, reptiles, etc.
LAM versus Private Practice • Clientele - pet owner vs. scientist – different issues. • Individual care vs. herd health – depends on study, some rare & valuable strains/species. • Diagnostics – pursue if you have time, money, tools – write up interesting cases. • Hours / Schedule – usually less weekend work!
Where are the jobs? • Anywhere biomedical research is performed • Academia – both large and small programs • Pharmaceutical Companies • Biotech Companies • Hospitals • Government-Military-NIH • Public Health • Throughout the US / world
LAM has several advantages. • Diverse jobs • Flexible hours • Good pay
ACLAM is the governing college for laboratory animal veterinarians. • ACLAM = American College of Laboratory Animal Medicine
Other LAM organizations can also provide information. • American Society of Laboratory Animal Practitioners (ASLAP) • American Association of Laboratory Animal Science (AALAS) • Charles L. Davis Foundation for the Advancement of Veterinary and Comparative Pathology
Do I need to become ACLAM board-certified? • Maybe or maybe not for clinical jobs. • Mid-career veterinarians can be valuable LAM veterinarians due to their clinical, fiscal and “people” skills. • But salary range is higher if certified. • Board certification is usually required for higher-level administrative jobs.
How do I become ACLAM board-certified? • Qualification to take board exams can be done via either • a traditional residency “training” route • or a nontraditional “experience” route • First-author research publication • Certifying examination
The “training” route is very common, especially for recently-graduated veterinarians. • Residencies may have a: • Clinical focus: Learn LAM & administration of an animal research program. • Research focus (NIH): Pursue an MS or PhD • Combination focus
How do I find a residency training program? • Visit the ACLAM web site • http://www.aclam.org/education-and-training/training-programs • Talk to a lab animal vet • Do an externship…more info later.
Where are the residency programs located? Size of program varies from 1-2 trainees up to 10-12 trainees!
Externships can introduce vet students OR practicing veterinarians to LAM. • 2-12 weeks, during summer or the academic year • Flexible experience depending on interest • Room and board may be covered • May receive a small stipend for living expenses
Where can I find out more about externships? • Check ACLAM’s website: • http://www.aclam.org/career-outreach/career-pathways • Check ASLAP’s website: • http://www.aslap.org/careers • Consider academia, biotechnology, federal government, and primate centers.
If a residency is not right for you, consider ACLAM certification via the “experience route.” • Small colleges and contract laboratories may employ you even if you don’t have LAM experience. • Part-time may be a good start. • But be sure to find an experienced LAM mentor to learn from!