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Cellular biology-Why do we need to know this?

Cellular biology-Why do we need to know this?. Bushong. When an atom is ionized. Chemical binding properties change in large molecules: breakage or relocation of molecules…become abnormal Abnormal means Function improperly cease to function -impairment or death of cell.

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Cellular biology-Why do we need to know this?

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  1. Cellular biology-Why do we need to know this?

  2. Bushong

  3. When an atom is ionized • Chemical binding properties change • in large molecules: breakage or relocation of molecules…become abnormal • Abnormal means • Function improperly • cease to function -impairment or death of cell

  4. Damage is Reversible • Ionized atoms become neutral…How? • Molecules are mended by repair enzymes • Immediate response to radiation • Latent response • (Bushong) see Box 32-1

  5. RADIATION INTERACTS AT ATOMIC LEVEL • Atoms combine to form molecules • The body is made of macromolecules • What is the definition of macromolecules?

  6. With this kind of potential damage…. The government tends to get involved CHAPTER 9 SHERER

  7. YOU ARE RESPONSIBLE FOR DIFFERENTIATING BETWEEN • ICRP • NCRP • UNSCEAR • NAS/NRC-BEIR • NRC • EPA • FDA • OSHA

  8. What is the smallest element of protoplasm? • The cell • Which of the following macromolecules contain enzymes for repair? A) protein b) lipids c) carbs d) nucleic acids

  9. _____provides most of the cell’s energy DNA and RNA are two types of these What is function of lipids Carbohydrates Nucleic acids store energy component of membrane protects against cold and heat assists in digestive process components of substances such as hormones MORE QUESTIONS

  10. Tissues are groups of ? Organs are groups of ? System is a group of? An organism is? Cells tissues organs a human

  11. CELLULAR ANATOMY • Ribosomes • Mitochondria • Endoplasmic Reticulum • Lysosomes • Golgi Apparatus

  12. RADIATION BIOLOGY CHAPTER 6..an introduction-What do you already know?

  13. DO YOU REMEMBER BERGONIE AND TRIBONDEAU? Pg 102 (Sherer)

  14. TWO TYPES OF CELLS • Somatic • Germ

  15. MALIGNANT CELLS • Divide abnormally • increased amount of chromatin • increased amount of nuclear material • normal cells stay together (tissue) • some malignant cells break away to other tissues

  16. Direct effect • Where do you think the radiation hits to be given this name?

  17. INDIRECT EFFECT • What molecule to you think radiation hits? • Most interactions occur here • Forms free radicals which are chemical components that damage cells • Free radicals are a result of radiolysis of water

  18. FRACTIONATION • Dividing a dose of radiation into small amounts over a given time

  19. PROTRACTED DOSE • Dose delivered continuously but at a lower rate

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