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Oral Biology 5301

Oral Biology 5301. Bone growth and development Bone biology Educational objectives Exposure to basic concepts of bone biology Correlation of basic bone biology to clinical treatment Special considerations / implications of bone biology to dentistry.

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Oral Biology 5301

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  1. Oral Biology 5301 • Bone growth and development • Bone biology • Educational objectives • Exposure to basic concepts of bone biology • Correlation of basic bone biology to clinical treatment • Special considerations / implications of bone biology to dentistry

  2. Clinical Correlates of Bone Growth and Development • Facial skeletal development • Maxillary development • Mandibular development

  3. Clinical Correlates of Bone Growth and Development • Effect of congenital anomalies on facial growth and development • Effect of surgical correction of congenital anomalies on facial growth and development • Tooth development and retention influence on alveolar bone levels

  4. Clincal Correlates of Bone Growth and Development • Orthodontic tooth movement • Bone healing following tooth extraction • Bone response to alloplastic materials • Bone healing in approximation of dental implants

  5. Clinical Correlates of Bone Growth and Development • Bone grafting to treat dentoalveolar defects • Bone grafting to treat discontinuity defects • Fracture healing

  6. Cellular Growth • Hypertrophy • Hyperplasia • Secretion of extracellular material • Interstitial growth

  7. Embryologic Type of Bone • Endochondral • Intramembranous

  8. Functional Matrix Theory of Growth • “Growth of the face occurs as a response to the functional need and is mediated by the soft tissue in which the bone is embedded” • Soft tissues grow, bone and cartilage react

  9. Growth Control • Bone is the determinant of its own growth • Cartilage is the determinant of bone growth • Soft tissue matrix is the determinant of growth • All are controlled genetically

  10. Orthodontic Tooth Movement • Bone apposition and resorption • Effects on the pulp • Effects on the PDL • Effects on the tooth root

  11. Effects of Periosteum • Provision of undifferentiated mesechymal cells • Envelope to limit/regulate bone apposition

  12. CC: Noticed swelling in face on left side for two weeks HPI: Facial swelling Left lower lip “tingles” No pain or change in bite Introduction10 y.o. female 12/98

  13. Examination • Left lower facial swelling, without thrill/bruit • Lower vestibular swelling, L>R • No abnormal tooth mobility • Teeth 19-28 vital with EPT • CN II-XII grossly intact

  14. Problem list: Multilocular radiolucent lesion Teeth vital without resorption, displacement, or mobility Apparent cortical expansion Diff. Dx: Central Giant Cell Lesion Ameloblastomic Fibroodontoma Ameloblastoma Assessment

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