1 / 4

Patient characteristics (acute infection): longitudinal samples from 3 acutely infected patients

Patient characteristics (acute infection): longitudinal samples from 3 acutely infected patients. Very high viral loads ALT peaked then fell All 3 patients failed to clear HCV infection, and became chronically infected. Amplicons of HCV quasispecies analyzed. Regions studied.

evelyn-savage
Download Presentation

Patient characteristics (acute infection): longitudinal samples from 3 acutely infected patients

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Patient characteristics (acute infection): longitudinal samples from 3 acutely infected patients • Very high viral loads • ALT peaked then fell • All 3 patients failed to clear HCV infection, and became chronically infected

  2. Amplicons of HCV quasispecies analyzed Regions studied 5’ UTR: untranslated, very low variability, used for subtyping Core: translated, well conserved E1/E2: envelope, includes HVR1 hypervariable region DNA barcoding

  3. HCV hypervariable regions

More Related