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CLUB DRUGS

CLUB DRUGS. DANCE ‘TILL YOU DROP. MAJOR CLUB DRUGS. MDMA/ECSTASY GHB/GBL KETAMINE NITROUS OXIDE POPPERS LSD. MISCELLANEOUS DRUGS. 2C-B GBL – GAMMA BUTYL LACTONE DEXTROMETHORPHAN HERBAL ECSTASY MUSHROOMS. ESCTASY. MDMA METHYLENEDIOXYMETHAMPHETAMINE ADAM X-TC CLARITY ESSENCE

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CLUB DRUGS

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  1. CLUB DRUGS DANCE ‘TILL YOU DROP

  2. MAJOR CLUB DRUGS • MDMA/ECSTASY • GHB/GBL • KETAMINE • NITROUS OXIDE • POPPERS • LSD

  3. MISCELLANEOUS DRUGS • 2C-B • GBL – GAMMA BUTYL LACTONE • DEXTROMETHORPHAN • HERBAL ECSTASY • MUSHROOMS

  4. ESCTASY • MDMA • METHYLENEDIOXYMETHAMPHETAMINE • ADAM • X-TC • CLARITY • ESSENCE • STACY • LOVER’S SPEED • EVE

  5. DOSAGES • THRESHOLD – 30 MG • AVERAGE – 75-125 MG • LETHAL DOSE – 106 - ~ 6000MG

  6. MDMA ACTIONS • DURATION • PRIMARY EFFECTS 3-4 HRS • “CRASH” 2-6 HRS • HANGOVER • (MAY LAST UP TO 5 DAYS) • POST –MDMA DEPRESSION

  7. MECHANISM OF ACTION • DECREASES DOPAMINE RELEASE • INHIBITS REUPTAKE OF SEROTONIN • RELEASES SEROTONIN • RESEMBLES HYBRID AMPHETAMINE & MESCALINE

  8. COMMONCONTAMINANTS • CHALK • LSD • AMPHETAMINES • HEROIN • CAFEINE • KETAMINE • EPHEDRINE

  9. ECSTASYBEHAVIORAL EFFECTS • INCREASED ENERGY • EMPATHY TOWARD OTHERS • INCREASED AFFECTION • EMOTIONAL OPENNESS • PROFOUND POSITIVE FEELINGS • EUPHORIA • DECREASED INHIBITIONS • DECREASED ANXIETY • EXTREME RELAXATION

  10. MDMA ACUTE EFFECTS • TEETH CLENCHING • NAUSEA • HALLUCINATION • CHILLS • SWEATING • TREMORS • BLURRED VISION • MUSCLE CRAMPING

  11. ACUTE SIDE EFFECTS • HYPERTHERMIA • INCREASED BODY TEMPERATURE • DEHYDRATION • CARDIOVASCULAR STIMULATION METABOLIC ACIDOSIS • RHAMDOMYOLOSIS • MUSCLE BREAKDOWN

  12. ACUTE TOXICITY • HYPERTHERMIA • CONVULSIONS • DISSEMINATED INTRAVASCULAR COAGULATION • ACUTE RENAL FAILURE • CARDIAC ARRYTHMIAS • HEPATITIS

  13. MDMA OVERDOSE • HIGH BLOOD PRESSURE • FAINTNESS • PANIC ATTACKS • LOSS OF CONSCIOUSNESS • SEIZURES • HEART FAILURE • HEAT STROKE

  14. MDMA AFTER EFFECTS • ANXIETY • PARANOIA • DEPRESSION

  15. MDMA PERMANENT DAMAGE • DEPRESSION • ANXIETY • MEMORY LOSS • CHANGES IN SLEEP PATTERNS • LEARNING IMPAIRMENTS • EMOTIONAL PROBLEMS

  16. MDMA TOXICITY • SIMILAR TO HEAT STROKE • URINARY pH LESS THAN 5.6 IN METABOLIC ACIDOSIS • CAUSES MYOGLUBIN CASTS • HYPERKALEMIA RELATED TO CARDIAC ARRYTHMIA • WATER INTOXICATION

  17. NEUROTOXICITY • NEURONAL DAMAGE • DECREASE IN DOPAMINE • LOSS OF SEROTONIN NERVE TERMINALS • PARKINSONISM • APPETITE SUPPRESSION

  18. PROTECTIVE MEASURES? • VIAGRA FOR SEXUAL PROBLEMS • SSRIs e.g. PROZAC • DRUGS THAT BLOCK DA RELEASE • ANTIOXIDANTS

  19. GHB • GAMMA HYDROXYBUTYRATE • LIQUID X, GREVIOUS BODILY HARM • CNS DEPRESSANT • ALSO USED BY BODY BUILDERS • SALTY TASTING LIQUID • ONSET OF ACTION 10-20 MIN • EFFECTS LAST UP TO 4 HOURS • CLEARED QUICKLY

  20. GHB USES • INTOXICATING PROPERTIES • SEDATIVE ACTIONS • EUPHORIC EFFECTS • RELIEVE ANXIETY • PRODUCE RELAXATION • GH RELEASING PROPERTIES

  21. GHB OVERDOSE • DROWSINESS • NAUSEA/VOMITING • HEADACHE • LOSS OF CONSCIOUSNESS • LOSS OF REFLEXES • IMPAIRED BREATHING • COMA/DEATH

  22. GHB DANGERS • DROWSINESS • DIZZINESS • NAUSEA • UNCONSCIOUSNESS • SEIZURES • SEVERE RESPIRATORY DEPRESSION • COMA • DEATH

  23. GHB WITHDRAWAL • ANXIETY • RESTLESSNESS • INSOMNIA • RAPID HEART BEAT • NAUSEA

  24. GHB DEATH LIST

  25. KETAMINE • SEDATIVE-HYPNOTIC • SPECIAL k & k • GENERAL ANESTHETIC • HALLUCINOGEN • ANALGESIC • RAPID ONSET • LASTS ~ ONE HOUR

  26. KETAMINE EFFECTS • IMPAIRED COORDINATION • IMPAIRED JUDGEMENT • PERISTENT MEMORY PROBLEMS • PSYCHOTIC SYMPTOMS • DREAMLIKE STATES • HALLUCINATIONS • NEAR DEATH EXPERIENCE (K-HOLE) • SENSORY IMPAIRMENT

  27. NITROUS OXIDE • LAUGHING GAS • DISSOCIATIVE ANESTHETIC • AVAILABLE IN “WHIPPITS” • INHALED FROM TANK OR BALLOONS • EFFECTS IMMEDIATE & SHORT-LIVED

  28. NITROUS EFFECTS • EUPHORIA • ANALGESIA • LOSS OF CONSCIOUSNESS

  29. ADVERSE EFFECTS • TEMPORARY LOSS OF MOTOR CONTROL • SENSATIONS & PERCEPTIONS DISCONNECTED • DREAMY MENTAL STATE • MILD AUDIO & VISUAL HALLUCINATIONS

  30. DANGERS • COLD GAS BURNS LIPS, THROAT, LUNGS • HYPOXIA • LONG-LASTING NUMBNESS IN EXTREMITIES

  31. POPPERS AMYL NITRATE/BUTYL NITRATE • RELAX SMOOTH MUSCLE • PRODUCE FEELING OF “RUSH” • FLUSHING • DIZZINESS • HEADACHE • PROGRESSIVE LOSS OF CONSCIOUSNESS

  32. LSD • POTENT HALLUCINOGEN • ERGOT FUNGUS • 30 g DOSE • ONSET WITHIN 30-90 MIN • “HIGH” LASTS 6-12 HOURS

  33. LSD EFFECTS • DILATED PUPILS • HIGHER BODY TEMPERATURE • INCREASED HEART RATE • INCREASED BLOOD PRESSURE • SWEATING • DRY MOUTH • TREMORS • NUMBNESS/WEKNESS

  34. LSD ACTIONS • DILATED PUPILS • INCREASED BODY TEMPERATURE • INCREASED HEART RATE • INCREASED BLOOD PRESSURE • LOSS OF APPETITE • INCREASED SWEATING • DRY MOUTH • TREMORS

  35. “BAD TRIP” • TERRIFYING THOUGHTS • SEVERE AGITATION • FEAR OF LOSING CONTROL • FEAR OF INSANITY & DEATH • SEVERE ANXIETY • SUICIDAL THOUGHTS • PRECIPITATE PSYCHOSIS • ACCIDENTAL DEATH

  36. LSD PSYCHOSIS • AFFECT PERCEPTION OF REALITY • INABILITY TO THINK RATIONALLY • DRAMATIC MOOD SWINGS • VIVID VISUAL DISTURBANCES • HALLUCINATIONS

  37. HALLUCINOGEN PERSISTINGPERCEPTION DISORDER (HPPD) • EPISODIC VISUAL DISTURBANCES • “FLASHBACKS” • FALSE FLEETING PERCEPTIONS • FLASHES OF COLOR • GEOMETRIC PSEUDOHALLUCINATIONS • POSITIVE AFTERIMAGES • PERMANENT ALTERATION IN VISUAL SYSTEM

  38. PCP • DEVELOPED IN 1950 • WAS USED AS IV ANESTHETIC • DISSOCIATIVE “OUT OF BODY” • PRODUCES DELIRIUM • EXTREME AGITATION • RAPID ONSET • LASTS FOR SEVERAL HOURS

  39. PCP ACTIONS • DISRUPTS NMDA RECEPTORS • AFFECT GLUTAMATE ACTIVITY • GLUTAMATE ROLE IN PAIN, COGNITION, LEARNING & MEMORY • ALSO AFFECTS DA CAUSING EUPHORIA OR “RUSH”

  40. PCP EFFECTS • SHALLOW RAPID BREATHING • INCREASED BLOOD PRESSURE • INCREASED HEART RATE • ELEVATED TEMPERATURE • NAUSEA • BLURRED VISION • DECREASED PAIN AWARENESS

  41. PCP EPISODE • DETACHEMENT FROM REALITY • DISTORTION OF TIME/SPACE • ALTERED BODY IMAGE • FEELING INVULNERABLE • EXAGGERATED STRENGTH • SEVERE DISTORIENTATION • SUICIDAL BEHAVIOR

  42. DEXTROMETHORPHAN • OTC COUGH MEDICINE • NMDA ANTAGONIST • DISSOCIATIVE EFFECTS

  43. ROHYPNOL • FLUNITRAZEPAM • ROOFIES • ILLEGAL IN US • TASTELESS/ODORLESS • 1 MG DOSE LASTS 8-12 HOURS

  44. ROHYPNOL ACTIONS • SEDATIVE EFFECTS 10X THAN VALIUM • EFFECTS APPEAR 15-20 MIN • LAST 4-6 HOURS • RESIDUAL EFFECTS UP TO 12 HOURS

  45. ROHYPNOL USES • BOOST HIGH FROM ALCOHOL • BOOST HIGH FROM HEROIN • MODULATE COCAINE EFFECTS • RAVE DRUG • “DATE RAPE” DRUG

  46. ROHYPNOL ADVERSEEFFECTS • LOSS OF MOTOR CONTROL • LACK OF COORDINATION • SLURRED SPEECH • CONFUSION • GI DISTRESS • RESPIRATORY DEPRESSION • IMPAIRED COGNITION • AMNESIA

  47. METHAMPHETAMINE EFFECTS • MEMORY LOSS • VIOLENCE • PSYCHOTIC BEHAVIOR • CARDIAC ARRYTHMIAS • NEUROLOGICAL DAMAGE

  48. METH TOXICITY • REDUCTION IN DA TRANSPORTERS • MASSIVE RELEASE OF DA & NE

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