The Rockefeller University Center for Clinical and Translational Science (CCTS)

1. The Rockefeller University Center for Clinical and Translational Science (CCTS) Maija Neville, MPH Administrative Director Center for Clinical and Translational Science The Rockefeller University Mneville@rockefeller.edu

2. Goal of The Rockefeller University Center for Clinical and Translational Science • Translate new scientific discoveries into improved health

3. Administration • Insure Rockefeller University compliance with all regulatory, financial and award related administration of the Center for Clinical and Translational Science (CCTS) • Plan and execute all NIH competing and non-competing applications and site visits

4. Administration Continued… • Insure active participation in all national oversight and subcommittees of NCRR/NIH as they pertain to CTSA • Recruit new faculty and staff • Insure protection of human subjects and patient safety • Provide oversight of high quality research

5. Center for Clinical and Translational Science James Krueger, MD Barry Coller, MD Sarah Schlesinger, MD Co-Prin. Investigator/ Prin. Investigator/ KL2 Co-Director Co-Director Project Director Maija Neville, MPH Administrative Director Maritza Puello, BA Justin O' Connor, BA CCTS Administrative Coord. Clinical Assistant Translational Science Training Participant/Clinical Clinical Research Informatics Biostatistics Immunophenotyping Interaction Office Core CCTS Administrative Structure

6. Committee StructureAdvisory Committee for Clinicaland Translational ScienceACCTS Oversight of Core Scientific Resources Biomedical Informatics Research Study Design & Biostatistics Research Education, training & Career Development Inter- institutional Collab., Recruitment, & Community Engagement Participant & Clinical Interaction Resources Protection of Human Subjects, Regulatory Issues & GCP Oversight of Pilot & Collaborative Translational & Clinical Studies Technology Transfer and Private Sector Partnering

7. CCTS Success • Development of CCTS web page and e-Newsletter • NYS Approval to confer the Master’s Degree in Clinical and Translational Science • Development of IND assistance Program • Increase BERD, IND, Informatics, GCP support • Launching of a project to validate research subject perception of participation instrument in partnership with NRC + Picker

8. CCTS Success • Development of KL2 Virtual application room • Production of iRIS Study management tool and Review board products • Expansion of Community Engagement, Recruitment and Outreach Activities (CDN)

9. CCTS Success • Establishment of a Department of Clinical Research Coordinators (CRC) within PCIR • Utilization CTSA resources to support language translation services

10. CCTS Success • Development of Immune monitoring core facility • Development of metabolic assessment laboratory • 4 KL2 Clinical Research Scholars • 2 new Medical Students • 9 Pilot Projects Funded

11. Barriers/Challenges • Staffing • Implementation of an effective community outreach program • Budgetary changes (indirect cost rate change, 2.9% reduction in U award)

12. Moving Forward • Complete staff recruitments • Continue progress in Information Technology, governance, and communication • Continue to develop a core of highly trained CRC’s • Ongoing enhancement of community outreach and participant recruitment • Focus on Clinical Scholar and faculty recruitment • Continue collaboration across CTSAs and with NIH/NCRR

13. Thank You Questions???