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Seminar 07

Seminar 07. Spine-Type-Specific Recruitment of Newly Synthesized AMPA Receptors with Learning. nuclei TO-PRO-3 |anti-GFP antibody. DOX (+) Home cage. DOX (+) 24 hrs FC. DOX (-) Home cage. DOX (-) 24 hrs FC. Novel context alone can induce c-fos promoter in CA1 field.

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Seminar 07

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  1. Seminar 07 Spine-Type-Specific Recruitment of Newly Synthesized AMPA Receptors with Learning

  2. nuclei TO-PRO-3 |anti-GFP antibody DOX (+) Home cage DOX (+) 24 hrs FC DOX (-) Home cage DOX (-) 24 hrs FC

  3. Novel context alone can inducec-fos promoter in CA1 field

  4. DiI crystals to label dendrites

  5. New GluR1 found onsome dendritic spine heads

  6. Anatomical classification of spines

  7. FC transiently increases % mushroom spines with new GluR1

  8. No difference between apical and basal CA1 dendrites

  9. Extinction protocol

  10. Extinction of contextual FC

  11. Extinction learning actually prolongs requirement for new GluR1

  12. No changes in the density of spines or the distribution of spine types

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