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Early Treatment: cases. David Baker East Sydney Doctors. Ron – 2011. 34 year old gay male HIV +ve 2011 CD4 = 570, VL = 102 000 One partner who is HIV +ve Not wanting treatment Otherwise well. Ron – 2014. No regular follow-up Herpes zoster CD4 = 470 Starting ARVs. Greg - 2013.
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Early Treatment:cases David Baker East Sydney Doctors
Ron – 2011 • 34 year old gay male • HIV +ve 2011 • CD4 = 570, VL = 102 000 • One partner who is HIV +ve • Not wanting treatment • Otherwise well
Ron – 2014 • No regular follow-up • Herpes zoster • CD4 = 470 • Starting ARVs
Greg - 2013 • 57 year old gay male • HIV +ve 1997 • Long term HIV –ve partner • Reluctant patient – rarely attends • CD4 = 660 • VL undetectable
Jack- 2014 • 62 year old heterosexual male • Long term HIV –ve partner • Otherwise well • CD4 = 718 • VL = 7800
Jason • 32 year old gay male, single • HIV +ve 2 weeks ago • Has booked 5 month holiday starting in 3 weeks • CD4 = 521 • VL = 4500
Peter • 33 year old gay male • HIV +ve 4 months ago in Melbourne • Moving to Sydney • Long term HIV –ve partner • CD4 = 789 • VL = 48000 • Wants trial of natural therapies
Tim • 44 year old gay male • HIV +ve 2 years • Single, multiple partners • CD4 = 620 • VL = 89 000 • Weekend alcohol and crystal binges • Wants to sort out drug problem before starting treatment
SR • 26 yr old male, FTE, stable accommodation, Brazilian with Australian residency • HIV positive Sept 2012 (HIV neg May 2012) • Admitted to SVH Aug 2012 with febrile illness but nil HIV test (? Sinusitis) • Possible rUPAI early Aug (2 x CMP in Ibeza) – states nil ejaculation “thought he was being careful”) • CD4 480, HIV VL 38,000
SR • Repeat pathology Oct 2012 • CD4 556 (31%), VL 22,600 • Treatment options were actually discussed at this time but not interested as yet • Also not interested in further counselling / groups – worried about other people knowing about his diagnosis
SR • Repeat pathology March 2013 • CD4 535 (21%), VL 63,000 • Seborrhoiec dermatitis, rosacea (Dermatology review) • Rectal and pharyngeal gonococcal PCR positive (states ‘brief’ rUPAI) • Anxious about physical appearance • Concerned he might have lymphadenopathy • Worried that all physical symptoms linked to HIV • Requests to commence treatment
Issues ? Against • CD4 count above 500 (following initial count) • ? Young age and lifelong treatment (? wait a few years) ? Fully informed • ? Side effects (what key points to discuss) ? For • Recent STI demonstrates ongoing sexual risk - ? public health issue • Individual health benefits (? What to tell him)
Alternatively • 26 yr old male, same results • Unemployed, Newstart • Currently ‘living with friends’ • Using $50 methamphetamine daily IV • Regular rUPAI
For • Public health issues • ? Individual health benefits Against • Compliance and possible resistance • Financial