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Antiviral for Influenza. Impact of Antiviral Therapy on Influenza Complications in Nursing Home Residents, Canada. Percent. Bowles et al. J Amer Geriatric Society 50: 608, 2002. Use of the Selective Oral Neuraminidase Inhibitor Oseltamivir to Prevent Influenza.
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Impact of Antiviral Therapy on Influenza Complications in Nursing Home Residents, Canada Percent Bowles et al. J Amer Geriatric Society 50: 608, 2002
Use of the Selective Oral Neuraminidase Inhibitor Oseltamivir to Prevent Influenza
The incidence of Adamantane and Neuraminidase Inhibitor Resistance among Clade 1 and Clade 2 • Clade 1 H5N1 viruses: • All Resistant • Clade 2 H5N1 viruses: • Sensitive - in most recent isolates • Resistant – in some isolates from Indonesia Adamantane : Amantadine/Rimantadine • Clade 1 H5N1 viruses: • Sensitive to oseltamivir & Zanamivir • Several mutants resistant to oseltamivir • Clade 2 H5N1 viruses • All sensitive to oseltamivir & Zanamivir NA inhibitor : Oseltamivir/Zanamivir
INLUENZA TERMASUK PENYAKIT YANG MEMILIKI PROPORSI PENULARAN INFEKSI SEBELUM MUNCUL SIMTOM ATAU PENULARAN OLEH INFEKSI YANG ASIMTOMATIK TINGGI (40-50%) Reproductive rate (Ro = 3) INFLUENZA TERMASUK TIDAK AKAN MUDAH DIKENDALIKAN DENGAN ISOLASI DAN CONTACT TRACING SARS SARS TIDAK MENULAR PADA MASA INKUBASI Reproductive rate (Ro=1,7) TERMASUK PENYAKIT YANG POTENSIAL DAPAT DIKENDALIKAN DENGAN ISOLASI DAN CONTACT TRACING INFLUENZA BERBEDA DENGAN SARS Factors that make an infectious diseases outbreak controllable. Proc.of Nat. Acad.Sci. 2004,101;6146-6151