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Genomic Databases. Cédric Notredame. Databases The Next Generation. Cédric Notredame. HOT !!!. VERY HOT !!!. ENSEMBL. TRANSFAC. KEGG. GENECARD. DIP, BIND. Gene Ontology: Words to describe all this. ANNOTATION. -Where are the genes ?. -What do they do: Biochemistry ?.
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Genomic Databases Cédric Notredame
Databases The Next Generation Cédric Notredame
HOT !!! VERY HOT !!!
ENSEMBL TRANSFAC KEGG GENECARD DIP, BIND Gene Ontology: Words to describe all this
ANNOTATION -Where are the genes ? -What do they do: Biochemistry ? -When do they do it: Regulation ? -Who do they do it for: Metabolic ?
What is inside the resource Gory Details Biological Questions You Can Ask Alternative Ressources
ENSEMBL: Where is my Gene in the Human Genome (who are its neighbors) ?
Using ENSEMBL www.ensembl.org
Using ENSEMBL: Asking a question What are the Neighbours of the DUT GeneIn the Human Genome ?
Using ENSEMBL: Asking a question What are the genes, on chromosome 1, that have been linked to a disease, and for which SNPs (Single Nucleotide Polymorphisms) have been identified?
Using ENSEMBL: Asking a question Select a Chromosome
Using ENSEMBL: Asking a question Select your filter
Using ENSEMBL: Asking a question Select The Information You Need
ENSEMBL Questions What are the Neighbours of the DUT GeneIn the Human Genome ? What are the genes, on chromosome 1, that have been linked to a disease, and for which SNPs (Single Nucleotide Polymorphisms) have been identified?
ENSEMBL: Watch Out Your Transcript of Interest May not be mapped Use Sim4 All the potential alternative splice forms are not always mapped Exons may be lost
ENSEMBL: A Few Alternative Resources www.ncbi.nlm.nih.gov NCBI genome.ucsc.edu UCSC www.genome.ad.jp GenomeNet
ENSEMBL TRANSFAC KEGG GENECARD DIP, BIND Gene Ontology: Words to describe all this
TRANSFAC: Who Turns On My Gene?
TRANSFAC Introducing TRANSFAC
Using TRANSFAC What are the transcription Factor Classes that contain a Zinc Finger
Using TRANSFAC What is Known about the ACE2 Transcription Factor
Using TRANSFAC What is The Specificity of my Factor
TRANSFAC: A Few Related Resources www.epd.isb-sib.ch
TRANSFAC: A Few Alternative Resources prodoric.tu-bs.de PRODORIC GenomeNet www.cbrc.jp/research/db/TFSEARCH.html
ENSEMBL TRANSFAC KEGG GENECARD DIP, BIND Gene Ontology: Words to describe all this
KEGG: Where Does My Protein Work?
KEGG Introducing KEGG
2003 2004
KEGG How Does it Work ?