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Cancer

Cancer. Cells Gone Wild!. Cancer Cell. Surrounded by T-cells and dead. How are cancer cells different from most cells?. Do not have a normally functioning cell cycle Divide excessively and can invade other tissue. Tumor. Abnormal mass of cells Skin Lung.

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Cancer

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  1. Cancer Cells Gone Wild!

  2. Cancer Cell • Surrounded by T-cells and dead

  3. How are cancer cells different from most cells? • Do not have a normally functioning cell cycle • Divide excessively and can invade other tissue

  4. Tumor • Abnormal mass of cells • Skin Lung

  5. Normal vs . Tumor Growth

  6. Benign Vs. Malignant • Benign-mass of normal cells at original site • Malignant- cancerous and can spread to other cells

  7. Tumor • Abnormal mass of cells

  8. Metastasis • Spread of cancer cells beyond their original site

  9. Metastasis of prostate tumor cells • Into bone cells

  10. Carcinogens • Any substance involved in the promotion of cancer: • gamma rays, X-rays, UV rays • Dioxin (pesticide) • Tobacco smoke • Asbestos • HPV virus

  11. Cancers are named • According to the tissue or organ in which they originate

  12. 4 types of Cancers • Carcinomas • Sarcomas • Lymphomas • Leukemias

  13. Carcinomas • Cancers that originate on external or internal coverings (skin, lining of intestine)

  14. Carcinoma Forming

  15. Sarcomas • Arise in tissue that support the body (bone and muscle)

  16. leukemia • cancer in leukocytes (white blood cells) in bone marrow • (too many white blood cells and not enough red blood cells)

  17. lymphomas malignant cells in the lymph system

  18. Lymphatic System • Works with circulatory system to filter clear fluid • (transports white blood cells) • Lymphatic System You Tube

  19. Cancer Populations

  20. Cancer Gene Checker • The p53 Tumor Suppressor Gene Triggers Cell Suicide

  21. FYI p27 on chromosome 12 • Inhibitor of cdk regulator of cell cycle • High levels of p27 shown in breast cancers

  22. Normal Cell Divisions • Mammalian Cells will divide about 50 times in a culture

  23. 3 ways to treat cancer • 1. Surgically remove • 2. Radiation • 3. Chemotherapy

  24. Surgically Removal

  25. Radiation Treatment • To kill cancer cells Usually X-rays and gamma rays to target the cancer cells

  26. Chemotherapy Drugs

  27. Cancer Fighting Drugs: work on mitotic spindles • TAXOL • Paclitaxol • Freezes the mitotic spindles after it forms • From Yew plant • VINBLASTIN • Prevents mitotic spindles from forming • From periwinkle

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