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Tory Davis, PA-C. Undernutrition. Malnutrition. Undernutrition and overnutrition Undernutrition can result from inadequate ingestion of nutrients, malabsorption, impaired metabolism, loss of nutrients due to diarrhea, or increased nutritional requirements (as in cancer or infection).
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Tory Davis, PA-C Undernutrition
Malnutrition Undernutrition and overnutrition Undernutrition can result from inadequate ingestion of nutrients, malabsorption, impaired metabolism, loss of nutrients due to diarrhea, or increased nutritional requirements (as in cancer or infection).
Stages of Undernutrition Each takes time to develop First, nutrient levels in blood and tissues change Second, intracellular changes in biochemical functions and structure Finally, signs and symptoms
Risk Factors Ages and stages Social circumstances: poverty Medical conditions
Infancy and Childhood High demands for: Vit E Energy Essential nutrients Nutrients req’d for nl body fxn that we can’t produce – must be obtained by diet Vegan mother breastfeeding B12 deficiency
Adolescence Anorexia Rapid growth
Pregnancy Fe deficiency anemia Folate deficiency anemia Pica – seen more in pregnancy – want to eat things that aren’t normally considered food – sometimes to replace nutrional deficit
Old Age Sarcopenia (progressive loss of lean body mass) begins at 40! physical activity food intake Anorexia cytokine levels androgen levels Basic metabolic rate
Disorders/Procedures DM – can’t absorb GI Tract disorders Malabsorptions, IBD,Bowel resection Impaired absorption of fats. Fat-sol vitamins, B12, Ca, Fe Liver d/o Impair metabolism of vit A, B12, protein
Disorders/Procedures Renal disorders Deficiencies of protein, vit D, Fe Increased metabolic demands Infection, trauma, fevers, burns
Diets Vegetarian B12 in vegans Fe defic in ovo-lacto Protein Fad diets Protein, vit, minerals Ask Liberace
Diet Meds/drugs/supplements Alter appetite Alter absorption and metabolism Etoh/Drugs Neglect of nutritional needs Etoh deficiencies of Mg, Zinc, thiamine Thus the “banana bag (mg, zinc thiamine + others).” Why? – see note below
Diagnosis of Undernutrition Hx: dietary intake, weight change, above risk factors SHx: money for food? Able to prepare meals? Think elders! PE: BMI, look for signs of deficiencies OR conditions that could predispose to undernutition. Like what? Jaundice, spoon nails, wasted, pale (sign of anemia), hair loss or thinning, etc MNA- Mini Nutritional Assessment
Testing- Labs Serum albumin as indirect measure May indicate protein deficiency Other testing- Vitamin/mineral levels as specific tests
PEM Protein Energy Malnutrition Energy deficit secondary to chronic deficiency of all macronutrients Graded mild to severe, based on percentage of expected wt Primary- inadequate intake Secondary from drug or d/o that interferes with nutrient use
PEM Developing countries: Children who can’t consume enough protein and calories Lack of access Developed countries: Institutionalized elderly Abuse (child or elder) Pts with decreased appetite or impaired digestion/absorption/metabolism
Vitamins Organic compound required as nutrient in tiny amounts but can’t be synthesized by the organism and must be obtained via diet. See posted vitamin chart for sources, functions, effects of deficiencies
Vitamin Deficiencies in developed countries Poverty Food faddism Drugs (ie drug/vit interactions) Alcoholism Parenteral nutrition (prolonged or with inadequate supplementation)
S/S Nutritional Deficiency: General Wasting Cachexia Energy deficiency
Skin Rash many vits (usually def), zinc, fatty acids Rash in sun-exposed areas Niacin (pellagra) Easy bruising Vit C or K
Hair/nails Thinning or loss of hair Protein Premature whitening of hair Selenium Spooning of nails Iron
Eyes Impaired night vision and Corneal keratomalacia Vit A
Mouth Cheilosis (angular cheilitis) and glossitis Riboflavin, niacin, pyridoxine, iron Bleeding gums Vitamin C, riboflavin
Extremities Edema Protein def Why?
Neuro Stocking/glove paresthesias and numbness Thiamin Tetany Ca, Mg Cognitive and sensory deficits Thiamin, niacin, B12
MSSK Wasting Protein Bony deformities Vit D, Ca Bone tenderness Vit D Joint pain/swelling Vit C
GI Diarrhea Protein, niacin, folic acid, B12 Diarrhea with dysgeusia Zinc Dysphagia/odynophagia (Plummer-Vinson syndrome) Iron
Endo Thyromegaly Iodine