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Onchocerciasis

Onchocerciasis. Katherine Swift Ph.D Student Walden University PUBH-8165-3 Instructor Dr. Raymond Thron Spring, 2009. River Blindness. (Worldbank,2002). Map of the region. Africa 30 countries Senegal Malawi Latin America Yemen (Worldbank,2002). Life cycle of Onchocerca volvulus.

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Onchocerciasis

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  1. Onchocerciasis Katherine Swift Ph.DStudent Walden University PUBH-8165-3 Instructor Dr. Raymond Thron Spring, 2009

  2. River Blindness (Worldbank,2002)

  3. Map of the region Africa 30 countries Senegal Malawi Latin America Yemen (Worldbank,2002)

  4. Life cycle of Onchocerca volvulus (WHO,2009)

  5. The black fly vector Simulium black fly Microfilariae 220 – 360 µm in length (WHO,2009)

  6. The Human Host The female and male worms entwine Female worm lengths range from 30 to 80 cms Male length ranges from 3 to 5 cm The female will release 1000 microfilariae (WHO,2009)

  7. Diagnosis • Skin snips • Blood samples • Eye examinations (WHO/TDR,2003)

  8. Microfilaia Cutaneous Tissues

  9. Imaging Studies • (WHO/TDR,2003)

  10. Characteristics

  11. Vision Loss • (Who/TDR,2003)

  12. Onchodermatitis • Depigmentation • Subcutaneous nodules • Lichenified dermatitis • Chronic papular dermatitis • Lymphadenopathy • Atrophy of skin • Onchocercomata • WHO/TDR,2003)

  13. Vector Elimination • (Who,2009)

  14. Treatment • Ivermectin (Mectizan®). WHO/TDR,2003)

  15. Special permission granted from The CarterCenter/Emily Straub Foundation The Carter Center

  16. Newer Therapeutic Strategies Wolbachia Species Doxycycline (WHO/TDR,2003)

  17. Global Partnerships to Eliminate Riverblindness (WHO/APOC,2007)

  18. Global Partnerships and Program • APOC • OCP

  19. The African Program for Riverblindness Control • (WHO/TDR,2003)

  20. Community Distributed Treatment with Ivermectin (COMDT) (WHO/APOC, 2007)

  21. COMDT • (WHO/APOC,2007)

  22. Future Work • (WHO/APOC,2007)

  23. Thank-you

  24. References • The Carter Center. The global 2000 river blindness. River Blindness News. 1999; 11:1-8 • Eezzuduemhoi, D. R., & Wilson, D. (2008). Onchocerciasis. Retrieved April 5, 2009, from eMedicine Ophthalmology Web site: http:/​/​emedicine.medscape.com/​article/​1204593 • Kazdins-Helds, J. K., Remme, J. H. F., & Boakye, B. (2003). Focus: Onchocerciasis. Nature Reviews Microbiology, 1(3), 178-180. doi:10.1038/​nrmicro779 • Sinha, S., Schwartz, R. A., & Kapilia, R. (2006). Onchocerciasis. Retrieved April 5, 2009, from eMedicine Infectious Diseases Web site: http:/​/​emedicine.medscape.com/​article/​224309

  25. References • WHO. (2009). Life-cycle of Onchocerca volvulus. Retrieved April 11, 2009, from African Programme for Onchocerciasis Control (APOC) Web site: http:/​/​www.who.int/​apoc/​onchocerciasis/​lifecycle/​en/​print.html • WHO. (2009). Vector elimination. Retrieved March 13, 2009, from African Programme for Onchocerciasis Control (APOC) Web site: http:/​/​www.who.int/​apoc/​vector/​en • WHO. (n.d.). APOC African Programme for Onchocerciasis Control. In Partners Meeting Report (JAF12.10, p. 37). Retrieved April 12, 2009, from www.who.int/​entity/​apoc/​publications/​yaounde_report_2006/​en/​index.html • WHO/​APOC. (2007). African Programme for Onchocerciasis Control Revitalizing health care delivery in sub-Saharan Africa (first ed., Vol. 1) [Brochure]. Retrieved April 19, 2009, from WHO Web site: http:/​/​www.who.int/​apoc/​publications/​cdti_healthsystems/​en/​index.html

  26. References • WHO/​TDR. (2003, November 28). TDR Image Library. Retrieved April 12, 2009, from TDR fro research on diseases and poverty Web site: http:/​/​apps.who.int/​tdr/​publications/​tdr-image-library • Worldbank. (2002). Global Partnership to Eliminate River blindness. Retrieved April 11, 2009, from Africa Program for Onchocerciasis Control Web site: http:/​/​www.worldbank.org/​afr/​gper

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