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Nurse Licensure Examination Review. Diabetes Mellitus. Diabetes Mellitus. A group of metabolic diseases characterized by elevated levels of glucose in the blood resulting from defects in insulin secretion, insulin action, insulin receptors or any combination of conditions. Diabetes Mellitus.
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Nurse Licensure Examination Review Diabetes Mellitus
Diabetes Mellitus • A group of metabolic diseases characterized by elevated levels of glucose in the blood resulting from defects in insulin secretion, insulin action, insulin receptors or any combination of conditions.
Diabetes Mellitus • A chronic disorder of impaired glucose metabolism, protein and fat metabolism
Diabetes Mellitus • BASIC PATHOLOGY : Insulin problem (deficiency or impaired action)
Diabetes Mellitus • Insulin is a hormone secreted by the BETA cells of the pancreas • Stimulus of insulin- HYPERGLYCEMIA
Diabetes Mellitus • Action of insulin: it promotes entry of Glucose into the body cells by binding to the insulin receptor in the cell membrane
INSULIN : Physiology Insulin Metabolic Functions: • 1. Transports and metabolizes GLUCOSE • 2. Promotes GLYCOGENESIS • 3. Promotes GLYCOLYSIS • 4. Enhances LIPOGENESIS • 5. Accelerates PROTEIN SYNTHESIS
Diabetes Mellitus RISK FACTORS for Diabetes Mellitus • 1. Family History of diabetes • 2. Obesity • 3. Race/Ethnicity
Diabetes Mellitus RISK FACTORS for Diabetes Mellitus • 4. Age of more than 45 • 5. Previously unidentified IFG/IGT • 6. Hypertension
Diabetes Mellitus RISK FACTORS for Diabetes Mellitus • 7. Hyperlipidemia • 8. History of Gestational Diabetes Mellitus
Diabetes Mellitus CLASSIFICATION OF DM 1. Type 1 DM • Insulin dependent Diabetes Mellitus 2. Type 2 DM • Non-insulin dependent Diabetes Mellitus 3. Gestational DM • Diabetes Mellitus diagnosed during pregnancy 4. DM associated with other conditions or syndromes
Diabetes Mellitus CLASSIFICATION OF DM 1. Type 1 DM • Insulin dependent Diabetes Mellitus
Diabetes Mellitus CLASSIFICATION OF DM 2. Type 2 DM • Non-insulin dependent Diabetes Mellitus
Diabetes Mellitus CLASSIFICATION OF DM 3. Gestational DM • Diabetes Mellitus diagnosed during pregnancy
Diabetes Mellitus CLASSIFICATION OF DM 4. DM associated with other conditions or syndromes
Diabetes Mellitus Other types of DM • 1. Impaired Glucose Tolerance • 2. Impaired Fasting Glucose • 3. Pre-diabetes
TYPE 1- Diabetes Mellitus This type of DM is characterized by the destruction of the pancreatic beta cells
TYPE 1- Diabetes Mellitus Etiology: 1. Genetic susceptibility- HLA DR3 and DR4 2. Autoimmune response 3. Toxins, unidentified viruses and environmental factors
TYPE 1- Diabetes Mellitus PATHOPHYSIOLOGY • Destruction of BETA cells decreased insulin production uncontrolled glucose production by the liver hyperglycemia signs and symptoms
TYPE 1- Diabetes Mellitus PATHOPHYSIOLOGY CLASSIC P’s • Polyuria • Polydipsia • Polyphagia
TYPE 2- Diabetes Mellitus • A type of DM characterized by insulin resistance and impaired insulin production
TYPE 2- Diabetes Mellitus Etiology: 1. Unknown 2. Probably genetic and obesity
TYPE 2- Diabetes Mellitus PATHOPHYSIOLOGY • Decreased sensitivity of insulin receptor to insulin less uptake of glucose HYPERGLYCEMIA
TYPE 2- Diabetes Mellitus PATHOPHYSIOLOGY • Decreased insulin production diminished insulin action hyperglycemia signs and symptoms
TYPE 2- Diabetes Mellitus PATHOPHYSIOLOGY • BUT (+) insulin in small amount prevent breakdown of fats DKA is unusual
GESTATIONAL Diabetes Mellitus • Any degree of glucose intolerance with its onset during pregnancy • Usually detected between 24-28th week gestation
GESTATIONAL Diabetes Mellitus • Blood glucose returns to normal after delivery of the infant • NEVER administer ORAL HYPOGLYCEMIC AGENTS to PREGNANT MOTHERS!
Diabetes Mellitus ASSESSMENT FINDINGS • 1. Classic 3 P’s • 2. Fatigue • 3. Body weakness
Diabetes Mellitus ASSESSMENT FINDINGS • 4. Visual changes • 5. Slow wound healing • 6. Recurrent skin and mucus membrane infections
Diabetes Mellitus DIAGNOSTIC TESTS • 1. FBS- > 126 • 2. RBS- >200 • 3. OGTT- > 200
Diabetes Mellitus DIAGNOSTIC TESTS • 4. HgbA1- for monitoring!! • 5. Urine glucose • 6. Urine ketones
Diabetes Mellitus DIAGNOSTIC CRITERIA • 1. FBS equal to or greater than 126 mg/dL (7.0mmol/L) • (Normal 8 hour FBS- 80-109 mg/dL)
Diabetes Mellitus DIAGNOSTIC CRITERIA • 2. OGTT value 1 and 2 hours post-prandial equal to or greater than 200 mg/dL • Normal OGTT 1 and 2 hours post-prandial- is • 140 mg/dL
Diabetes Mellitus DIAGNOSTIC CRITERIA • 3. RBS of equal to or greater than 200 mg/dL PLUS the 3 P’s
Diabetes Mellitus NURSING MANAGEMENT OF DM • The main goal is to NORMALIZE insulin activity and blood glucose level by:
Diabetes Mellitus NURSING MANAGEMENT OF DM 1. Nutritional modification 2. Regular Exercise 3. Regular Glucose Monitoring 4. Drug therapy 5. Client Education
Diabetes Mellitus The Patient with DM • HISTORY • Symptoms and characteristics • PHYSICAL EXAMINATION • VS, BMI, Fundoscopy, Neuro • LABORATORY EXAMINATION • FBS, RBS, HgbA1c, lipid profile, ECG, UA • REFERRALS • Ophthalmologist, Podiatrist, Dietician, etc..
Diabetes Mellitus The Patient with DM • HISTORY • Symptoms and characteristics • PHYSICAL EXAMINATION • VS, BMI, Fundoscopy, and Neuro assessment
Diabetes Mellitus The Patient with DM • LABORATORY EXAMINATION • FBS, RBS, HgbA1c, lipid profile, ECG, and Urinalysis • REFERRALS • Ophthalmologist, Podiatrist, Dietician, etc..
Diabetes Mellitus NUTRITIONAL MANAGEMENT • 1.Review the patient’s diet history to identify eating habits and lifestyle • 2. Coordinate with the dietician in meal planning for weight loss
Diabetes Mellitus NUTRITIONAL MANAGEMENT • 3. Plan for the caloric intake distributed as follows- CHO 50-60%; Fats 20-30%; and Proteins 10-20% • 4. Advise moderation in alcohol intake • 5. Using artificial sweeteners is acceptable
Diabetes Mellitus EXERCISE Management • 1. Teach that exercise can lower the blood glucose level • 2. Diabetics must first control the glucose level before initiating exercise programs.
Diabetes Mellitus EXERCISE Management • 3. Offer extra food /calories before engaging in exercise • 4. Offer snacks at the end of the exercise period if patient is on insulin treatment.
Diabetes Mellitus EXERCISE Management • 5. Advise that exercise should be done at the same time every day, preferably when blood glucose levels are at their peak
Diabetes Mellitus EXERCISE Management • 6. Regular exercise, not sporadic exercise, should be encouraged. • 7. For most patient, WALKING is the safe and beneficial form of exercise
Diabetes Mellitus GLUCOSE MONITORING • Self-monitoring of blood glucose (SMBG) enables the patient to adjust the treatment regimen to obtain optimal glucose control
Diabetes Mellitus GLUCOSE MONITORING • Most common method involves obtaining a drop of capillary blood applied to a test strip. • The usual recommended frequency is TWO-FOUR times a day.