DRUGS USED FOR COPD

1. DRUGS USED FOR COPD BY :DR .ISRAA OMAR

2. INTRODUCTION • COPD is a major global health problem . • Cigarette smoking is the main cause, and is increasing in the developing countries as a result of targeting by tobacco industry . • Air pollution, also etiologically important, is also increasing, and there is huge unmet need for effective treatment • Despite this COPD has been received relatively little attention compared to asthma

3. Principle of treatment • Stop smoking slow the progression of COPD • Immunization against influenza and Pneumococci • Glucocorticoids are generally ineffective like in asthma • Short and long acting bronchodilators can provide useful palliation in patient with reversible component

4. continue • Theophylline can be given orally but of uncertain benefit • Doxapram (respiratory stimulant) are sometimes used to in patient who developed respiratory failure but have largely been replaced by ventilatory support • long term oxygen therapy at home prolong life in patient with sever disease and hypoxemia if they stop smoking only to avoid oxygen fire

5. Acute exacerbation • Treated with inhaled oxygen (24-28%) • Avoid giving high concentration of oxygen so not to terminate the hypoxic drive which will lead to CO2 retention • Broad spectrum antibiotics including activity against haemophilus influnzae

6. Thank you

7. referrence • Rang and dale pharmacology