1 / 7

Supplementary Fig. 1

Supplementary Fig. 1. NCI/ADR-RES. OVCAR-8. DXR. 4μM SM:. - + - + - +. PTEN. p53. p130Cas. β -actin. Supplementary Fig. 2. 4μM SM:. mock CA-Stat3. – + – +. p-Stat3. p-Stat3/actin:. Stat3. Cyclin D1. cyclinD1/actin:. Skp2.

gail
Download Presentation

Supplementary Fig. 1

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Supplementary Fig. 1 NCI/ADR-RES OVCAR-8 DXR 4μM SM: - + - + - + PTEN p53 p130Cas β-actin

  2. Supplementary Fig. 2 4μM SM: mock CA-Stat3 – + – + p-Stat3 p-Stat3/actin: Stat3 Cyclin D1 cyclinD1/actin: Skp2 Skp2/actin: p27Kip1 p27Kip1/actin: β-actin

  3. Supplementary Fig. 3 SM (μM) : 0 1 2 4 EGF SM (μM) : 0 1 2 4 A B p-Stat3 (Y705) p-EGFR (Y1068) Stat3 EGFR β-actin p-JAK2 (Y1007/1008) JAK2 β-actin

  4. Supplementary Fig. 4 * A B NCI/ADR-RES OVCAR-8 NCI/ADR-RES DXR OVCAR-8 DXR 4μM SM: - + - + - + 4μM SM: - + - + - + OVCAR-8 MDR-1 MDR-1 24hr β-actin β-actin MDR-1 72hr D β-actin NCI/ADR-RES C Cont DMSO 4μM SM DXR Rhodamin123 accumulation

  5. Supplementary Fig. 5 OVCAR-8 DXR 4μM SM: - + - + c-myc β-actin

  6. Supplementary Fig. 6 OVCAR-8 DXR 24 48 72 24 48 72 (hr) 4μM SM: - + - + - + - + - + - + Skp2 p-Akt (S473) Akt β-actin

  7. Supplementary Fig. 7 NCI/ADR-RES OVCAR-8 DXR 4μM SM: - + - + - + β-catenin β-actin

More Related