1 / 27

CATALYST

Using the symbolic representation for nucleotides (see board), draw a mini DNA molecule. Your drawing should meet the following requirements: Contain 6 nucleotides total Label A, T, C, and Gs Label the 5’ and 3’ ends of each DNA strand. CATALYST. TODAY: PROTEINS!.

gallagher-haren
Download Presentation

CATALYST

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Using the symbolic representation for nucleotides (see board), draw a mini DNA molecule. Your drawing should meet the following requirements: Contain 6 nucleotides total Label A, T, C, and Gs Label the 5’ and 3’ ends of each DNA strand CATALYST

  2. TODAY:PROTEINS!

  3. The Building Blocks of Proteins: AMINO ACIDS!

  4. R-groups affect Reactivity and Solubility

  5. Amino Acids as Buffers:

  6. How do Amino Acids Link Together to Form Proteins?

  7. Practice Peptide Bonding! • Draw two glycine amino acid molecules side by side (glycine’s R group is just “H” • Circle what atoms must be removed in order for a peptide bond to form • Draw the dipeptide that is formed

  8. DIRECTIONALITY!

  9. Protein Primary Structure

  10. Primary Structure  Secondary Structure! Hydrogen bonding!

  11. Secondary Structure  Tertiary Structure

  12. Tertiary Structure  Quaternary Structure (in some proteins) Hemoglobin’s Chemical Formula: C3032H4816O872N780S8Fe4

  13. Change in primary structure = Change in function! Mutated Cells

  14. Change in structure = Change in function!

  15. Change in structure = Change in function!

  16. Levels of Protein Structure – Group Demo

  17. Levels of Protein Structure • In your group of 3 – 4 people… • 1) Create a song / rap • 2) Include all 4 levels of protein structure and the types of bonds / attractive forces involved in each level

  18. From 20 building blocks… A HUGE DIVERSITY OF STRUCTURE!

  19. Two Main Categories: 1) FIBROUS • Structure: • Water insoluble • Very tough • Can be supple or stretchy • Parrallel chains in long fibers or sheets

  20. Two Main Categories: 1) FIBROUS • Function: • Structural support - collagen in connective tissue • Contractile – actin and myosin in muscles

  21. Two Main Categories: 2) GLOBULAR • Structure: • Water soluble • Tertiary / quaternary structure critical to function

  22. Two Main Categories: 2) GLOBULAR • Function: Protective (antibodies)

  23. Two Main Categories: 2) GLOBULAR • Function: Transport (aquaporins, hemoglobin)

  24. Two Main Categories: 2) GLOBULAR • Function: Catalytic (enzymes)

  25. Two Main Categories: 2) GLOBULAR • Function: Regulatory (hormone receptors)

  26. When Protein’s Go Awry = PRIONS! Normal Misfolded (Prion) • Scrapie • Kuru • Mad Cow

  27. Practice Free Response 10 points One of the unifying themes in biology is that function follows structure. Explain how the structure of proteins determines their function by responding to the following: Describe the structure of an amino acid (3) Outline the formation of a protein from its primary structure to its quaternary structure (4 points) Discuss the relationship between protein structure and function in fibrous and globular proteins (4)

More Related