Stereoisomers: Optical Isomers PART 2

1. Stereoisomers: Optical IsomersPART 2 CH21 Problem Solving Class

2. Sample Problem

3. Sample Problem S R S S enantiomers same S S R R same same

4. Review Problem

5. Review Problem

6. Diastereomers

7. Diastereomers

8. Sample Problem

9. Epimers: Special Diastereomers, different with ONE chiral center

10. Sample Problem:

12. Meso Compounds

13. Meso Compounds

14. Meso Compounds

15. Meso Compounds

16. Sample Problem

17. Sample Problem

18. Racemic Mixtures & Resolving

19. Racemic Mixtures & Resolving

20. Review of Isomerism

21. Stereochem of Reactions

23. Stereochem of Reactions

24. Sample Problem

25. Sample Problem

26. Sample Problem • Equal chance to attack both carbons from the top, vs. both carbons from the bottom, which means you’ll have 2 racemic pairs (50:50) • BUT THEN THESE RACEMIC MIXTURES aren’t 50:50 because of the methyl group in the ‘up’ position… meaning it won’t be a 25:25:25:25 mixture of all for, but a A:A:B:B ratio

27. Prochirality

28. Prochirality • Using our RIGHT HAND RULE, try to see if you can get a 1-2-3 with your right hand. The face where your thumb points to is the Re face! • Then with your left land, find 1-2-3, and you’ll find the Si face.

29. Prochirality • Using our RIGHT HAND RULE, try to see if you can get a 1-2-3 with your right hand. The face where your thumb points to is the Re face! • Then with your left land, find 1-2-3, and you’ll find the Si face.

30. Sample Problem

31. Sample Problem

32. Sample Problem

33. Sample Problem

34. Prochirality

35. Sample Problem

36. Sample Problem

37. Sample Problem

38. Sample Problem