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Suggested Readings: Transcription Voet and Voet: Ch 31 Watson: Ch12 pp. 437-362

Suggested Readings: Transcription Voet and Voet: Ch 31 Watson: Ch12 pp. 437-362. Central Dogma:. RTase .

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Suggested Readings: Transcription Voet and Voet: Ch 31 Watson: Ch12 pp. 437-362

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  1. Suggested Readings: Transcription Voet and Voet: Ch 31 Watson: Ch12 pp. 437-362

  2. Central Dogma: RTase 

  3. Figure 31-14 The two possible modes of RNA chain growth. Growth may occur (a) by the addition of nucleotides to the 3¢ end and (b) by the addition of nucleotides to the 5¢ end. Page 1226

  4. Rifampicin inhibits prokaryotic RNA POL by binding to the  subunit of RNA POL

  5. Figure 31-17 X-Ray structure of actinomycin D in complex with a duplex DNA of self-complementary sequence d(GAAGCTTC).Intercalates and inhibits both DNA and RNA Pol. Page 1229

  6. VVP Fig. 25-3

  7. VVP Fig. 25-6

  8. Figure 30-10 Schematic diagram for the nucleotidyl transferase mechanism of DNA polymerases. Page 1143

  9. Watson Fig. 8.6 Mechanism of Polymerase Action

  10. Mechanism for DNA pol Similar for RNA pol

  11. RNA Pol E. coli DNA Pol I Klenow Fragment E. coli

  12. Figure 31-11aX-Ray structure of Taq RNAP core enzyme. a subunits are yellow and green, b subunit is cyan, b¢ subunit is pink, w subunit is gray. Page 1224

  13. Figure 31-12a The sequence of a fork-junction promoter DNA fragment. Numbers are relative to the transcription start site, +1. Page 1225

  14. Figure 31-12b X-Ray structure of Taq holoenzyme in complex with a fork-junction promoter DNA fragment. Page 1225

  15. DNA Footprinting

  16. Figure 31-10 The sense (nontemplate) strand sequences of selected E. coli promoters. Page 1223

  17. Watson Figure 12-6

  18. Figure 31-13bModel of the open (Rpo) complex of Taq RNAP with promoter-containing DNA showing the transcription bubble and the active site. Page 1225

  19. Figure 31-13aModel of the closed (RPc) complex of Taq RNAP with promoter-containing DNA extending between positions –60 and +25. Page 1225

  20. Figure 31-15 RNA chain elongation by RNA polymerase. Page 1227

  21. Watson Figure 12-7

  22. Watson Figure 12-7

  23. VVP Fig. 25-8

  24. Figure 31-16 An electron micrograph of three contiguous ribosomal genes from oocytes of the salamander Pleurodeles waltl undergoing transcription. Page 1228

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