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Seascape is an Indo-US company working to foster international collaborative research, education, and software development in the fields of Drug Discovery and Nanotechnology. With over ten years of experience, Seascape operates from New Delhi and California, offering scientific community development, software support, project coordination, and more.
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Seascape Intro Indo-US company with a mission to foster international collaborative research, education and software knowledge development/dissemination in the areas of Drug Discovery and Nanotechnology. Operates from New Delhi and California and has been in operation for over ten years
Seascape Role Scientific Community Development & Integration in India and USA Scientific & Technical Support for Software & Collaborative R&D Projects New project searching, identification and matching with scientific skills in India and USA Scientific Support, co-ordination and project management Software support, co-ordination and management Education and Training
Seascape - Key People Sunil Chawla, Founder: B.Tech from IIT Kharagpur, India M.Engg. from McGill-Montreal (Cancer Research Thesis MBA from UC Berkeley Experience: Apple, GE and Oracle in USA Dr. Steve Bowlus, Comp Chemist Postdoctoral studies in toxicology and nutrition, University of Illinois MS, Ph.D, Organic Chemistry, University of Illinois, Urbana Dr. Indira Ghosh, JNU, Sci Advisor Dean, School of info Technology, JNU, New Delhi
Dr. Indira Ghosh, JNU Introduction Dr. Indira Ghosh, currently Dean of School of Information Technology, JNU, New Delhi is the Chief Investigator and Scientific Advisor working with Seascape on the OpenTox collaborative project
Dr. Indira Ghosh - Background More than a decade of experience working in leading pharmaceutical industry (Astra Zeneca, R&D Bangalore, India) Ph.D from prestigious Indian Institute of Science, Bangalore in the field of molecular biophysics. Ph.D work on the enzyme specificity with respect to the stereochemical aspects of ligands Ph.D thesis could be taken as initial scientific study towards the development of field known as ‘docking’ Post-doctoral appointment at University of Huston, Texas with Prof. J. A. McCammon (currently at University of California San Diego, USA) Worked on implementation of many complex algorithms in the filed of Molecular Dynamics, has contributed in development of free energy calculation using perturbation method
Recent/Relevant Research Research related to designing inhibitors for acting on H+ K+ ATPase, drug design (QSAR and toxicity prediction) for the lead series related to disease like tuberculosis and malaria, for more than a decade during her association with AstraZeneca. Currently, she is supervising major project related to force field development of Metalloprotease, excited state treatment of proton pumping phenomena of the ATPase funded by Ministry of Communication and Information Technology and Department of Biotechnology, Government of India.
Recent/Relevant Publications An Information–Theoretical Measure of Similarity and a Topological Shape and Size Descriptor for Molecular Similarity Analysis (IEJMD,3,350- 360, 2004) Developing an Antituberculosis Compounds Database and Data Mining in the Search of a Motif Responsible (minimum common bioactive substructure-MCBS) for the Activity of a Diverse Class of Antituberculosis Agents (J. Chem. Info. Model, 46, 17-23, 2006) Mapping Selectivity and Specificity of Active Site of Plasmepsins from Plasmodium falciparum Using Molecular Interaction Field Approach (Protein & Peptide Letters, 14, 569-574, 2007)