1 / 6

Enzymes

k 1. k 2. S. E. k -1. - K m , V max. 0.5 V max. K m. Enzymes. Eric Niederhoffer SIU-SOM. S. P. E. EI. S. E. K ic. S + E. ES. E + P. +. I. K m app / V max. K m app. -1/ K m app. Competitive Inhibition. CI. Competitive. ESI. K iu. S + E. ES. E + P. +. I.

gclayborne
Download Presentation

Enzymes

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. k1 k2 S E k-1 -Km, Vmax 0.5Vmax Km Enzymes Eric Niederhoffer SIU-SOM S P E

  2. EI S E Kic S + E ES E + P + I Kmapp/Vmax Kmapp -1/Kmapp Competitive Inhibition CI Competitive

  3. ESI Kiu S + E ES E + P + I 1/Vmaxapp 0.5Vmax Kmapp/Vmaxapp Kmapp -1/Kmapp Uncompetitive Inhibition Uncompetitive (catalytic) UCI S E

  4. EI ESI S E Kic Kiu S + E ES E + P + + I I 1/Vmaxapp Km/Vmaxapp 0.5Vmax Noncompetitive Inhibition NCI Noncompetitive (mixed-type) NCI S E

  5. Enzyme Inhibition Summary Neat or what?

  6. Review Questions • What is the function of enzymes? • What do enzyme names mean? • What are the types of enzyme inhibition (functional and graphical features)?

More Related