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The value of Frame-based CT guided stereotactic biopsy in the treatment of different brain tumors

Neurosurgery Clinic Clinical Centre of Vojvodina , Novi Sad Serbia. The value of Frame-based CT guided stereotactic biopsy in the treatment of different brain tumors. M. Karan MD P. Vulekovic MD PhD Dj. Jajic MD PhD T. Cigic Md PhD V . Papic MD PhD Dj . Djilvesi MD B. Jelaca MD.

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The value of Frame-based CT guided stereotactic biopsy in the treatment of different brain tumors

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  1. Neurosurgery Clinic Clinical Centre of Vojvodina, Novi Sad Serbia The value of Frame-based CT guided stereotactic biopsy in the treatment of different brain tumors M. Karan MD P. Vulekovic MD PhD Dj. Jajic MD PhD T. Cigic Md PhD V. Papic MD PhD Dj. Djilvesi MD B. Jelaca MD

  2. Introduction • Frame-based stereotactic brain biopsy is an effective way for acquiring histological diagnosis. • This diagnostic method reach all brain locations • It is appropriate for patients of all ages and medical conditions

  3. Aim • To evaluate results of the stereotactic biopsy in tretament of different intracranial lesions in our facility

  4. Material and methods • Retrospectiveresearchat the Clinical Center of Vojvodina • From January 2009 to December 2012 • 61 patients with different intracranial lesions • Age ranged from 16 to 81, mean age of 70,15 years • CT guided stereotactic biopsy in the general anesthesia

  5. Material and methods • Hystological diagnosis of deep intrinsic lesion • Diffuse, infiltrative or multiple lesions • Hystological diagnosis of intracranial lesion in patients in poor medical condition • Decompression and hystological diagnosis of cystic lesion • Indications

  6. Material and methods • Laboratory tests • CT scan • MRI, MRS • Informed consent • Preoperative preparation: • Frame placement • CT scan contrast agent • Coordinates • Transffer to the operating theater

  7. Material and methods • Standard Lexel stereotactic frame modified by Karl-Dieter Lerch • CL instruments GmbH, Germany

  8. Material and methods • Patient positioning • Partialy hair shaving • 14mm Burr hole • Aspiration biopsy 8-10 bits, side-cutting Sedan needle • Frozen section PH analisys • Paraffine embedded specimens • Control CT scan

  9. Results • Thalamus was the most common location (58%) of lesion. • Diagnostic yield was 100% • There were no transient or permanent neurological deficits after the procedure • Patients were discharged usually on the 4th or 5th postoperative day.

  10. Complications • There were no transient or permanent neurological deficits after the procedure • Karnofsky performance index was unchanged in all of our patients

  11. Conclusion • Frame-based stereotactic biopsy is safe and reliable procedure in the diagnosis and management of brain lesions

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